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2.A.20.2.2
High affinity Pi:Na+ symporter

Accession Number:P38361
Protein Name:YB8I aka Pho89 aka YBR296C aka YBR2113
Length:574
Molecular Weight:62654.00
Species:Saccharomyces cerevisiae (Baker's yeast) [4932]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate phosphate, Na+

Cross database links:

Genevestigator: P38361
eggNOG: fuNOG06320
HEGENOM: HBG325527
DIP: DIP-4966N
RefSeq: NP_009855.1   
Entrez Gene ID: 852599   
Pfam: PF01384   
KEGG: sce:YBR296C   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005315 F:inorganic phosphate transmembrane transport...
GO:0015319 F:sodium:inorganic phosphate symporter activity
GO:0006817 P:phosphate transport
GO:0055085 P:transmembrane transport

References (2)

[1] “Complete DNA sequence of yeast chromosome II.”  Feldmann H.et.al.   7813418
[2] “Identification, cloning and characterization of a derepressible Na+-coupled phosphate transporter in Saccharomyces cerevisiae.”  Martinez P.et.al.   9671031

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MALHQFDYIF AIAMLFAFLD AFNIGANDVA NSFASSISSR SLKYWQAMVL AGLCEFLGAV 
61:	LAGARVSGTI KNNIIDSSIF TNDPAVLMLT MTSALIGSSC WLTFATAIGM PVSTTHSIVG 
121:	GTIGAGIAAG GANGVVWGWS GVSQIIASWF IAPILAGAIA AIVFSISRFS VLEVKSLERS 
181:	IKNALLLVGV LVFATFSILT MLIVWKGSPN LHLDDLSETE TAVSIVLTGA IASIVYFIFF 
241:	YPFYRRKVLD QDWTLKLIDI FRGPSFYFKS TDDIPPMPEG HQLTIDYYEG RRNLGTTVSV 
301:	EDEENKAASN SNDSVKNKED IQEVDLVRTE TEPETKLSTK QYWWSLLKQG PKKWPLLFWL 
361:	VISHGWTQDV IHAQVNDRDM LSGDLKGMYE RSKFYDNRVE YIYSVLQAIT AATMSFAHGA 
421:	NDVANATGPL SAVYVIWKTN TIGAKSEVPV WVLAYGGVAL VIGCWTYGYN IIKNLGNKMI 
481:	LQSPSRGFSI ELAVAITTVM ATQLGIPTST TQIAVGGIVA VGLCNKDLKS VNWRMVAWCY 
541:	SGWFLTLPIA GLIAGIINGI ILNAPRFGVE YQMT