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2.A.21.2.5
Proline uptake porter, OpuE (YerK) (von Blohn et al. 1997).  Regulated by osmotic stress (high osmolarity).  Induction involves σB and σA (Spiegelhalter and Bremer 1998).

Accession Number:M1TZ79
Protein Name:Proline transporter OpuE
Length:492
Molecular Weight:53283.00
Species:Bacillus subtilis subsp. subtilis 6051-HGW [1147161]
Number of TMSs:13
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Proline

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  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
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  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSIEIIISLG IYFIAMLLIG WYAFKKTTDI NDYMLGGRGL GPFVTALSAG AADMSGWMLM 
61:	GVPGAMFATG LSTLWLALGL TIGAYSNYLL LAPRLRAYTE AADDAITIPD FFDKRFQHSS 
121:	SLLKIVSALI IMIFFTLYTS SGMVSGGRLF ESAFGADYKL GLFLTTAVVV LYTLFGGFLA 
181:	VSLTDFVQGA IMFAALVLVP IVAFTHVGGV APTFHEIDAV NPHLLDIFKG ASVISIISYL 
241:	AWGLGYYGQP HIIVRFMAIK DIKDLKPARR IGMSWMIITV LGSVLTGLIG VAYAHKFGVA 
301:	VKDPEMIFII FSKILFHPLI TGFLLSAILA AIMSSISSQL LVTASAVTED LYRSFFRRKA 
361:	SDKELVMIGR LSVLVIAVIA VLLSLNPNST ILDLVGYAWA GFGSAFGPAI LLSLYWKRMN 
421:	EWGALAAMIV GAATVLIWIT TGLAKSTGVY EIIPGFILSM IAGIIVSMIT KRPAKASYRL 
481:	FGVMEKLLKR KK