TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.21.2.6
High affinity proline-specific Na+:proline symporter, PutP (Rivera-Ordaz et al. 2013).  Proline is a preferred source of energy for this microaerophilic bacterium.  PutP is efficiently inhibited by the proline analogs, 3,4-dehydro-D,L-proline and L-azetidine-2-carboxylic acid.

Accession Number:O24896
Protein Name:Proline permease (PutP)
Length:496
Molecular Weight:54081.00
Species:Helicobacter pylori (strain ATCC 700392 / 26695) [85962]
Number of TMSs:13
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Proline, Na+

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MGHVVLSTPI VTMFIVYSLL MLYIGFYFYK QNETTEDYFL GDRSMGPVIS ALSAGASDMS 
61:	GWLLMGLPGA LYVGGLINSH IAIGLSLGAL INWVFVAKRL RIYTSVIANS ITISDYFETR 
121:	FSDDKHILRL ISAFVILIFF IFYISSGLVS GAKLFEATFG IQYTYALSIG TLIIVSYTFL 
181:	GGYKAVCWTD LIQGLLMMSA LIVVPIVMII HLGGIGEGIK IIREIKPENL SFLQGSSVVA 
241:	IISSLAWGLG YFGQPHILVR FMSIRSIRDV PKATTIGISW MVISLIGACV MGLLGVAYVH 
301:	KFDLSLEDPE KIFIVMSQLL FNPWITGILL SAILAAVMST ASSQLLVSSS TIAEDFYATI 
361:	FNKDAPQKLV MAISRLSVLG VACIAFFIST DRNASILSIV SYAWAGFGAS FGSVILFSLF 
421:	WSRMTRIGAI AGMLSGASTV ILYDKFGKSF LDIYEIVPGF IVASVAIVVF SLFSSVRTGT 
481:	KEAFETMLKE IESLKH