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2.A.21.3.10
Na+-dependent, smf-driven, sialic acid transporter, STM1128 (NanP) (Severi et al., 2010). Also transports the related sialic acids, N-glycolylneuraminic acid (Neu5Gc) and 3-keto-3-deoxy-d-glycero-d-galactonononic acid (KDN) (Hopkins et al. 2013). 

Accession Number:Q8ZQ35
Protein Name:Putative sodium/glucose cotransporter
Length:498
Molecular Weight:54777.00
Species:salmonella typhimurium [90371]
Number of TMSs:13
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Sialic acid

Cross database links:

HEGENOM: HBG359501
RefSeq: NP_460100.1   
Entrez Gene ID: 1252646   
Pfam: PF00474   
BioCyc: STYP99287:STM1128-MONOMER   
KEGG: stm:STM1128   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005215 F:transporter activity
GO:0006814 P:sodium ion transport
GO:0055085 P:transmembrane transport

References (1)

[1] “Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.”  McClelland M.et.al.   11677609

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MITHSFGIVN YLVLFGYLLA MMLVGVYFSR RQKTADDYFR GGGRVPGWAA GVSVFATTLS 
61:	SITFMSIPAK AFTSDWTFII GQYLAIAILP LVFYFYIPFF RKLKVTSAYE YLEARFDVRC 
121:	RLFASMSFML FHIGRIAIIT FLTVLALRPF IAIDPVILVL LISVMCIIYT WMGGIEGVIW 
181:	TDVIQGLLLS GSAILIFIVI CLKVQGGIDE IFTVTQQADK FFPATQFHWS WTESTVPVLM 
241:	IGFLFANIQQ FTASQDVVQR YIVTDSIEET KKTLLTNAKL VAVIPVFFFA IGSALFVYYQ 
301:	QHPQLLPAGF NTGGILPLFV VTEMPVGIAG LIIAAIFAAA QSSISSSLNS ISSCFNSDIY 
361:	QRLSHKKRTP ENRMKIAKLV ILVAGLISSA ASVWLVMADE SEIWDAFNSL IGLMGGPMTG 
421:	LFMLGIFFKR ANAGSAVLGI IISVITVLGA RYATDLNFFF YGVIGSLSVV ISGVIFAPLF 
481:	APAPPLTLDE KPEPKVTL