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2.A.21.3.15
Sodium/glucose cotransporter 5 (Na+/glucose cotransporter 5) (Solute carrier family 5 member 10)

Accession Number:A0PJK1
Protein Name:Sodium/glucose cotransporter 5
Length:596
Molecular Weight:64342.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:14
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Na+, glucose

Cross database links:

Genevestigator: A0PJK1
eggNOG: COG4146
HEGENOM: HOG000025422
Entrez Gene ID: 125206   
Pfam: PF00474   
KEGG: hsa:125206   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005215 F:transporter activity
GO:0006814 P:sodium ion transport
GO:0055085 P:transmembrane transport

References (4)

[1] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[2] “DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.”  Zody M.C.et.al.   16625196
[3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[4] “Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.”  Mayya V.et.al.   19690332

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MAANSTSDLH TPGTQLSVAD IIVITVYFAL NVAVGIWSSC RASRNTVNGY FLAGRDMTWW 
61:	PIGASLFASS EGSGLFIGLA GSGAAGGLAV AGFEWNATYV LLALAWVFVP IYISSEIVTL 
121:	PEYIQKRYGG QRIRMYLSVL SLLLSVFTKI SLDLYAGALF VHICLGWNFY LSTILTLGIT 
181:	ALYTIAGGLA AVIYTDALQT LIMVVGAVIL TIKAFDQIGG YGQLEAAYAQ AIPSRTIANT 
241:	TCHLPRTDAM HMFRDPHTGD LPWTGMTFGL TIMATWYWCT DQVIVQRSLS ARDLNHAKAG 
301:	SILASYLKML PMGLIIMPGM ISRALFPDDV GCVVPSECLR ACGAEVGCSN IAYPKLVMEL 
361:	MPIGLRGLMI AVMLAALMSS LTSIFNSSST LFTMDIWRRL RPRSGERELL LVGRLVIVAL 
421:	IGVSVAWIPV LQDSNSGQLF IYMQSVTSSL APPVTAVFVL GVFWRRANEQ GAFWGLIAGL 
481:	VVGATRLVLE FLNPAPPCGE PDTRPAVLGS IHYLHFAVAL FALSGAVVVA GSLLTPPPQS 
541:	VQIENLTWWT LAQDVPLGTK AGDGQTPQKH AFWARVCGFN AILLMCVNIF FYAYFA