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2.A.21.3.3
Nucleoside or glucose(?):Na+ symporter

Accession Number:P26430
Protein Name:SL52 aka SNST aka SLC5A2 aka SNST1
Length:672
Molecular Weight:73162.00
Species:Oryctolagus cuniculus (Rabbit) [9986]
Number of TMSs:14
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Nucleosides, glucose, Na+

Cross database links:

eggNOG: maNOG05228
RefSeq: NP_001076138.1   
Entrez Gene ID: 100009386   
Pfam: PF00474   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0015293 F:symporter activity
GO:0006814 P:sodium ion transport
GO:0055085 P:transmembrane transport

References (1)

[1] “Cloning and functional expression of a mammalian Na+/nucleoside cotransporter. A member of the SGLT family.”  Pajor A.M.et.al.   1740408

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MEEHMEAGSR LGLGDHGALI DNPADIAVIA AYFLLVIGVG LWSMCRTNRG TVGGYFLAGR 
61:	SMVWWPVGAS LFASNIGSGH FVGLAGTGAA NGLAVAGFEW NALFVVLLLG WLFAPVYLTA 
121:	GVITMPQYLR KRFGGHRIRL YLSVLSLFLY IFTKISVDMF SGAVFIQQAL GWNIYASVIA 
181:	LLGITMVYTV TGGLAALMYT DTVQTFVIIA GAFILTGYAF HEVGGYSGLF DKYMGAMTSL 
241:	TVSEDPAVGN ISSSCYRPRP DSYHLLRDPV TGDLPWPALL LGLTIVSGWY WCSDQVIVQR 
301:	CLAGRNLTHI KAGCILCGYL KLTPMFLMVM PGMISRILYP DEVACVAPEV CKRVCGTEVG 
361:	CSNIAYPRLV VKLMPNGLRG LMLAVMLAAL MSSLASIFNS SSTLFTMDIY TLRPRAGEGE 
421:	LLLVGRLWVV FIVAVSVAWL PVVQAAQGGQ LFDYIQSVSS YLAPPVSAVF VVALFVPRVN 
481:	EKGAFWGLIG GLLMGLARLI PEFSFGTGSC VRPSACPAFL CRVHYLYFAI VLFFCSGLLI 
541:	IIVSLCTAPI PRKHLHRLVF SLRHSKEERE DLDADELEAP ASPPVQNGRP EHAVEMEEPQ 
601:	APGPGLFRQC LLWFCGMNRG RAGGPAPPTQ EEEAAAARRL EDINEDPRWS RVVNLNALLM 
661:	MAVAMFFWGF YA