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2.A.21.6.4
Probable histatin 5 antimicrobial peptide uptake system. May also take up spermidine and be required for morphogenesis (Mayer et al., 2012).

Accession Number:Q59VF2
Protein Name:Potential urea active transport protein
Length:725
Molecular Weight:79582.00
Species:Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) [237561]
Number of TMSs:15
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate peptides, Spermidine

Cross database links:

eggNOG: COG0591
HEGENOM: HBG397209
Entrez Gene ID: 3644730    3644760   
Pfam: PF00474   
KEGG: cal:CaO19.781    cal:CaO19.8403   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0015606 F:spermidine transmembrane transporter activity
GO:0006814 P:sodium ion transport
GO:0015840 P:urea transport

References (1)

[1] “The diploid genome sequence of Candida albicans.”  Jones T.et.al.   15123810

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MADSYVPLPQ SAGYAVVVGL GFVFAFGMML TTYILRRYNK EVMTAEEFAT AGRSVKTGLI 
61:	AACIVSSWTW SATLNGSTSQ VYNNGVCGSI FYAMGATVQI TLFACLAIKA RERAPAAHTY 
121:	LEIVKGRYGT TTHFVYIFWG IVTNILVTSM LLSGGSATVN DLTGMNIVAA ILLLPLGVVI 
181:	YTLFGGIKAT FLTDYAHTVV LIVIIFIFAF TTWATSSKLG SPQAVWEIVT KLAESNPREG 
241:	NAGGSYFTMH SRSGGMFFVI NIIGNFGTVF LDNGYFNKAF AANPSSTYKG YIFGSLAWCA 
301:	IPALCSLTMG FAALALEHTE YWPLGRPMTA AEVASGLVLP NAASALLGKA GAVLALLMVF 
361:	MAVTSAMSAE LIAVSTIATY DIYRTYINPN ASGKKLIWVS HLSTVIFAYT MAGFAIGLYY 
421:	AKVSMGYLYE MMGVIIGGAV LSSALTILSK RQNWHAATFT PIISTALAIM AWLVCTKKKF 
481:	GSVTYLKTFE DDAMLTGNCV ALLTPFIIVP ILTFIFKPQN FDWKLLDQRI TRVDEEEELA 
541:	EALGGTVSSD PERLHPIKSQ ISVIASQLVE GEREQYQKEK EILNKSFKIC CIVCCTLAIC 
601:	LVVLFPMPLY GTKYIFSKKF FTGWVVVFII WLFYSAFQVI IFPIWESRTD LYHTFRGIYW 
661:	DLTGQTYKLK AWQNEHPEEM HAVRSQLQAQ LSRTAVTHEI VDGKAFGDGY VTPANIDDAL 
721:	EEKKG