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2.A.21.7.3
Pyruvate/acetate/propionate: H+ symporter, MctC (DhlC; cg0953).

Accession Number:Q8NS49
Protein Name:Na+/proline, Na+/panthothenate symporter or related permease
Length:551
Molecular Weight:57268.00
Species:Corynebacterium glutamicum [1718]
Number of TMSs:13
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate pyruvate, Acetate, Propionate, H+

Cross database links:

HEGENOM: HBG533958
RefSeq: NP_600062.1    YP_225125.1   
Entrez Gene ID: 1018828    3343485   
Pfam: PF00474   
BioCyc: CGLU196627:CG0953-MONOMER   
KEGG: cgb:cg0953    cgl:NCgl0799   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005215 F:transporter activity
GO:0006814 P:sodium ion transport
GO:0055085 P:transmembrane transport

References (1)

[1] “The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins.”  Kalinowski J.et.al.   12948626

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MNSTILLAQD AVSEGVGNPI LNISVFVVFI IVTMTVVLRV GKSTSESTDF YTGGASFSGT 
61:	QNGLAIAGDY LSAASFLGIV GAISLNGYDG FLYSIGFFVA WLVALLLVAE PLRNVGRFTM 
121:	ADVLSFRLRQ KPVRVAAACG TLAVTLFYLI AQMAGAGSLV SVLLDIHEFK WQAVVVGIVG 
181:	IVMIAYVLLG GMKGTTYVQM IKAVLLVGGV AIMTVLTFVK VSGGLTTLLN DAVEKHAASD 
241:	YAATKGYDPT QILEPGLQYG ATLTTQLDFI SLALALCLGT AGLPHVLMRF YTVPTAKEAR 
301:	KSVTWAIVLI GAFYLMTLVL GYGAAALVGP DRVIAAPGAA NAAAPLLAFE LGGSIFMALI 
361:	SAVAFATVLA VVAGLAITAS AAVGHDIYNA VIRNGQSTEA EQVRVSRITV VVIGLISIVL 
421:	GILAMTQNVA FLVALAFAVA ASANLPTILY SLYWKKFNTT GAVAAIYTGL ISALLLIFLS 
481:	PAVSGNDSAM VPGADWAIFP LKNPGLVSIP LAFIAGWIGT LVGKPDNMDD LAAEMEVRSL 
541:	TGVGVEKAVD H