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2.A.21.9.2
The proline sensor-receptor domain of the PrlS sensor kinase

Accession Number:Q93N33
Protein Name:PrlS
Length:1156
Molecular Weight:126672.00
Species:Aeromonas hydrophila [644]
Number of TMSs:13
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Proline

Cross database links:

Pfam: PF02518    PF00512    PF00072   

Gene Ontology

GO:0016020 C:membrane
GO:0005524 F:ATP binding
GO:0005215 F:transporter activity
GO:0000156 F:two-component response regulator activity
GO:0000155 F:two-component sensor activity
GO:0018106 P:peptidyl-histidine phosphorylation
GO:0006355 P:regulation of transcription, DNA-dependent
GO:0007165 P:signal transduction
GO:0055085 P:transmembrane transport
GO:0000160 P:two-component signal transduction system (p...

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MHQGWLLIGM SLAYLGLLFL IAFVADKSKR RRLKGQPLLY SLSLAVYCTS WTFFGTVGQA 
61:	SESPWSPVPI YLGPMLVFLF GWRLLARLIL VAKREHITSI ADFIAARYGK SQRLAMVITL 
121:	IAVMGILPYL VLQLKAIVTG LDMLMANSVP VGPTGNTGGL ALGVTMILAL FSILFGTRNL 
181:	DATEHHRGMV VAIAFESLVK LLAFMAVGGF ALWLIIAKPS QARTLVASDF LDAVVAVSPG 
241:	SLLELAIYTL VAMCAVICLP RQFHVTVVEN NQGQDLHWAR WVFPLYLFLM GLFIWPLALA 
301:	GKQWVGAGMG SDTYVISLPM SLGYDGMAML AFLGGTSAAT GMVIVCTIAL AIMVSNDLVL 
361:	PVLLRRFWQQ GRDERLMRLL LQVRRGAILL ILLAAWALYL WLGDLTSLSR IGYLSFGAVA 
421:	QFAPALLLGL YWRHGNRKGV YLGLSLGVSL WFLTLLAESG LLAGSPLEAL LAPPNWPAFR 
481:	DLSLGAWCIF ISLLLNLVGY VAGSLLSRAA VSERLQAANF VGKPSQDQAA LYQARVSVKE 
541:	LEMLAARFVG SSRVKRAFGR FAGEHGGTLA PQMQASADLI AHTERLLAGV FGTSSARLVL 
601:	ASALQGRNMQ LEEIATIVDE ASDVFRFNRG LLQGAIEHMG QGISVVDREL KLVAWNRRYI 
661:	ELFHYPPGLI QVGRSIEEII RYNAEQGLCG PGELEAHVAR RVAFMQRGSP HVSARERPDG 
721:	RVIEMQGNPM PAGGFVMTFT DITPFRAAER VLREANEHLE ARVAERTHEL NRQLLLVNQQ 
781:	VERANHSKSR FLAAVSHDLT QPLNAAKLFT SSLLEMLPGV QGAEQRAEQV RIARHIDDAL 
841:	GATEDLITDL LDISRLEAGK FKAKKLDFAL REVFDNLKAE FGVLAQAGDI QFSVVESKLA 
901:	VYSDVRLLRR VLQNFLTNAF RYNPGGRVLL GCRRLGDKVR IEVWDNGPGI PLDKQEAIFD 
961:	EFSRLDHSRT AREQGLGLGL AIARGISLVL GHPLSLRSWP QAGSVFSITL NLATRPVMPT 
1021:	QVAAPAVRDS QLEGIKILCI DNEEDILTAM HSLLGRWGCE VVCAQSLAQA EDLIAGGFLP 
1081:	RLVLSDYHLD DGKTGLQALH MIRLAHGNEI GGIIISADRK SELQAQIREH GYGYVSKPVK 
1141:	PLKLRALMNS LLLPIA