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2.A.23.1.3
C4-dicarboxylate transporter (substrates: fumarate, D- and L-malate, succinate, succinamide, orotate, iticonate, mesaconate)

Accession Number:Q01857
Protein Name:DctA
Length:444
Molecular Weight:46045.00
Species:Rhizobium leguminosarum [384]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Fumarate, malate, Succinamide, Orotate, Iticonate, Mesaconate

Cross database links:

Pfam: PF00375   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0017153 F:sodium:dicarboxylate symporter activity
GO:0008643 P:carbohydrate transport
GO:0006835 P:dicarboxylic acid transport

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MIAAPLDAVA GSKGKKPFYS HLYVQVLVAI AAGILLGHFY PELGTQLKPL GDAFIKLVKM 
61:	IIAPVIFLTV ATGIAGMSDL QKVGRVAGKA MLYFLTFSTL ALIIGLIVAN VVQPGAGMNI 
121:	DPASLDPAAV ATFAAKAHEQ SIVGFLTNII PTTIVGAFAD GDILQVLFFS VLFGIALAMV 
181:	GEKGEQVVNF LNSLTAPVFK LVAILMKAAP IGAFGAMAFT IGKYGVGSIA NLAMLIGTFY 
241:	ITSLLFVFIV LGAVARYNGF SIVALLRYIK EELLLVLGTS SSEAALPGLM NKMEKAGCKR 
301:	SVVGLVIPTG YSFNLDGTNI YMTLAALFIA QATGIHLSWG DQILLLLVAM LSSKGAAGIT 
361:	GAGFITLAAT LSVVPSVPVA GMALILGIDR FMSECRALTN LVGNAVATIV VARWENELDT 
421:	VQLAAALGGQ TGEDTSAAGL QPAE