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2.A.23.1.4
The L-cystine/L-selenocystine:H+ symporter, TcyP (YhcL) (Burguière et al., 2004)

Accession Number:P54596
Protein Name:TcyP (YhcL)
Length:463
Molecular Weight:48982.00
Species:Bacillus subtilis [1423]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Selenocystine, Cystine, H+

Cross database links:

HEGENOM: HBG739804
RefSeq: NP_388794.1   
Entrez Gene ID: 939257   
Pfam: PF00375   
KEGG: bsu:BSU09130   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0017153 F:sodium:dicarboxylate symporter activity
GO:0006865 P:amino acid transport
GO:0006835 P:dicarboxylic acid transport

References (4)

[1] “A 22 kb DNA sequence in the cspB-glpPFKD region at 75 degrees on the Bacillus subtilis chromosome.”  Noback M.A.et.al.   8969498
[2] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377
[3] “Global expression profile of Bacillus subtilis grown in the presence of sulfate or methionine.”  Auger S.et.al.   12193636
[4] “Three different systems participate in L-cystine uptake in Bacillus subtilis.”  Burguiere P.et.al.   15262924

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	METLLVVLHV FILFLLILGL FVMQKKHVSF SKRVFTALGL GIVFGFALQL IYGPTSNIVI 
61:	QTADWFNIAG GGYVKLLQMV VMPLVFISIL GAFTKLKLTK NLGKISGLII GILVATTAVA 
121:	AAVGIASALS FDLQAIQVDQ GSTELSRGQE LQQKSEDMTA KTLPQQIVEL LPGNPFLDFT 
181:	GARPTSTIAV VIFAAFLGVA FLGVKHKQPE QAETFKKLVD AVYAIVMRVV TLILRLTPYG 
241:	VLAIMTKTIA TSDLDSILKL GMFVIASYAA LITMFIIHLL LLTFSGLNPV IYLKKAVPVL 
301:	VFAFTSRSSA GALPLNIKTQ RSMGVPEGIA NFAGSFGLSI GQNGCAGIYP AMLAMMIAPT 
361:	VGQNPFDPVF IITVIAVVAI SSFGVAGVGG GATFAALLVL SSLNMPVALA GLLISIEPLI 
421:	DMGRTALNVS GSMTSGLITS KVTKEIDQGA FHDQSRVIEA EEA