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2.A.23.1.9
Fumarate:H+ symporter of 442 aas and 14 established TMSs, DctA. Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate.  The 3-d structure has been solved (Geertsma et al. 2015). It reveals an inward facing transmembrane domain of two 7 TMS intertwined inverted repeats similar to that of UraA as well as a STAS domain (Geertsma et al. 2015).

Accession Number:Q1J1H5
Protein Name:C4-dicarboxylate transport protein
Length:442
Molecular Weight:46367.00
Species:Deinococcus geothermalis (strain DSM 11300) [319795]
Number of TMSs:8
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Fumarate, H+, Succinate, malate

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MPKIFRSLYV QVLIAIVLGI LVGFLFPSFG EGLKPLGDGF IKLIKMLIAP IIFATVVSGI 
61:	AHMRDTKKVG RVGGKALIYF EVVTTFALVI GLVVANILKP GHGMNVNPAT LDTSAISKYT 
121:	QAAGEQSVAD FLLHIIPNTL VSAFTEGDLL QVLLISVLFG FALTQLGTLG QKVLAGIEAV 
181:	NSAVFVILGF VMRLAPIGAF GAMAFTIGKY GVGTLAQLAY LMVAFYATCL LFVFVVLGLI 
241:	ARFAGFSILK FIRFIKEELL LVLGTSSSES ALPRLITKLE YAGANRSVVG LVVPAGYSFN 
301:	LDGTSIYLTM ATLFIAQATN THLSLGQQLG ILGVLLLTSK GAAGVTGSGF ITLAATLSAV 
361:	GHVPVAGLAL ILGIDRFMSE ARALTNFVGN GVATLVIARS EKALDTNRLQ RVLNGEVLPP 
421:	ATPEVAAEER GEGRGLDGPL PA