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2.A.24.2.5
Citrate:acetate antiporter, CitW

Accession Number:Q8VS41
Protein Name:CitW
Length:454
Molecular Weight:48152.00
Species:Klebsiella pneumoniae [573]
Number of TMSs:13
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Citrate, Acetate

Cross database links:

Pfam: PF03390   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0008514 F:organic anion transmembrane transporter act...
GO:0015711 P:organic anion transport

References (1)

[1] “Identification of a gene cluster in Klebsiella pneumoniae which includes citX, a gene required for biosynthesis of the citrate lyase prosthetic group.”  Schneider K.et.al.   11948157

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSTTDNAFSA TLEPIDTPKT TLKQRWWHIM DNWKVGIVPL PLFLLAGGLI ALDCLGGKLP 
61:	SDIVVMVATL AFFGFACGEF GKRLPVLGKL GAAAICATFI PSALVHYGLL PDVVIESTTK 
121:	FYKSTNILYL YICCIIVGSI MSMNRTTLIQ GFLKIFFPML CGEVVGMLVG IGVGTLLGME 
181:	PFQVFFFIVL PIMAGGVGEG AIPLSMGYAA LMHMEQGVAL GRVLPMVMLG SLTAIVISGC 
241:	LNQLGKRFPH LTGEGQLMPN RSHETRSLSE SEGVSGKTDV GTLASGALLA VLLYMMGMLG 
301:	HKLIGLPAPV GMLFLAVLLK LANVVSPRLQ EGSQMVYKFF RTAVTYPILF AVGVAITPWQ 
361:	ELVNAFTLTN LLVIVSTVSA LVATGFLVGK KIGMHPIDVA IVSCCQSGQG GTGDVAILTA 
421:	GNRMSLMPFA QIATRIGGAI NVSLGLLFLS HYLA