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2.A.25.1.1
Alanine (or glycine):Na+ symporter

Accession Number:P30144
Protein Name:DagA
Length:542
Molecular Weight:59023.00
Species:Alteromonas haloplanktis [228]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Alanine, Glycine, Na+

Cross database links:

Pfam: PF01235   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005283 F:sodium:amino acid symporter activity
GO:0006865 P:amino acid transport
GO:0006814 P:sodium ion transport

References (1)

[1] “Identification and sequence of a Na(+)-linked gene from the marine bacterium Alteromonas haloplanktis which functionally complements the dagA gene of Escherichia coli.”  Macleod P.R.et.al.   1447975

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MLGGAVWFPY VLLGVGLFFT IYLKFPQIRY FKHACQVVSG KFDKKDTEGD TTHFQALATA 
61:	LSGTVGTGNI GGVALAISIG GPAALFWMWM TAFFGMTTKF VEVTLSHKYR EKTEDGTMSG 
121:	GPMYYMDKRL NMKWLAILFA VATVISSFGT GSLPQINNIA QGMEATFGFA PMATGAVLSI 
181:	LLALVILGGI KRIAAITSRV VPLMAAIYII GALAVIFYNA ENIGPSFSAV FMDAFSGSAA 
241:	AGGFLGASFA YAFNRGVNRG LFSNEAGQGS APIAHASAKA DEPVSEGIVS ILEPFIDTII 
301:	ICTLTGLVIL SSGVWNEKFQ THFERSAMSI IKGDYTEENQ TQREDLYKYL NGQKSNIETF 
361:	TGNIEVVNGE ALSTGFTVLH SRSIAEDVRF GITEKHKYTG VVEVIDGMPT DDSISLVGKS 
421:	LVHSAELTTK AFKRGYFGDS GQYIVSIGLL LFAFSTAIAW SYYGDRAMIY LLGHRSVMPY 
481:	RVFYVAAFFW ASFADTTLVW KLAAVAIVVM TLPNLIGIML LRKEMKESVD DYWVKFKKDN 
541:	EK