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2.A.25.1.5
Amino-acid carrier protein, AlsT.  Negatively regulated by TnrA (Yoshida et al. 2003).

Accession Number:Q45068
Protein Name:Amino-acid carrier protein AlsT
Length:465
Molecular Weight:50300.00
Species:Bacillus subtilis (strain 168) [224308]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Alanine

Cross database links:

eggNOG: COG1115
HEGENOM: HOG000255107
Entrez Gene ID: 938191   
Pfam: PF01235   
KEGG: bsu:BSU18120   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005283 F:sodium:amino acid symporter activity

References (4)

[1] “New genes in the 170 degrees region of the Bacillus subtilis genome encode DNA gyrase subunits, a thioredoxin, a xylanase and an amino acid transporter.”  Rose M.et.al.   8969507
[2] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377
[3] “Nucleotide sequence of an endo-beta-1,4-glucanase gene from Bacillus subtilis CK-2.”  Lindahl V.et.al.   7710280
[4] “Identification of additional TnrA-regulated genes of Bacillus subtilis associated with a TnrA box.”  Yoshida K.et.al.   12823818

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MESFFNSLIN IPSDFIWKYL FYILIGLGLF FTIRFGFIQF RYFIEMFRIV GEKPEGNKGV 
61:	SSMQAFFISA ASRVGTGNLT GVALAIATGG PGAVFWMWVV AAVGMASSFV ESTLAQLYKV 
121:	RDGEDFRGGP AYYIQKGLGA RWLGIVFAIL ITVSFGLIFN AVQTNTIAGA LDGAFHVNKI 
181:	VVAIVLAVLT AFIIFGGLKR VVAVSQLIVP VMAGIYILIA LFVVITNITA FPGVIATIVK 
241:	NALGFEQVVG GGIGGIIVIG AQRGLFSNEA GMGSAPNAAA TAHVSHPAKQ GFIQTLGVFF 
301:	DTFIICTSTA FIILLYSVTP KGDGIQVTQA ALNHHIGGWA PTFIAVAMFL FAFSSVVGNY 
361:	YYGETNIEFI KTSKTWLNIY RIAVIAMVVY GSLSGFQIVW DMADLFMGIM ALINLIVIAL 
421:	LSNVAYKVYK DYAKQRKQGL DPVFKAKNIP GLKNAETWED EKQEA