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2.A.26.1.1
Branched chain amino acid: Na+ symporter

Accession Number:P19072
Protein Name:BraB aka PA1590
Length:437
Molecular Weight:45283.00
Species:Pseudomonas aeruginosa [287]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Branched amino acids, Na+

Cross database links:

HEGENOM: HBG533860
RefSeq: NP_250281.1   
Entrez Gene ID: 882083   
Pfam: PF05525   
BioCyc: PAER208964:PA1590-MONOMER   
KEGG: pae:PA1590   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015658 F:branched-chain aliphatic amino acid transme...
GO:0015803 P:branched-chain aliphatic amino acid transport

References (2)

[1] “Cloning and nucleotide sequence of the gene braB coding for the sodium-coupled branched-chain amino acid carrier in Pseudomonas aeruginosa PAO.”  Hoshino T.et.al.   2111004
[2] “Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen.”  Stover C.K.et.al.   10984043

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTHLKGFDLL ALGFMTFALF LGAGNIIFPP SAGMAAGEHV WSAAFGFLLT GVGLPLLTVV 
61:	ALARVGGGIG RLTQPIGRRA GVAFAIAVYL AIGPLFATPR TAVVSFEMGV APFTGDGGVP 
121:	LLIYTVAYFS VVLFLVLNPG RLVDRVGKVI TPVLLSALLV LGGAAIFAPA GEIGSSSGEY 
181:	QSAPLVQGFL QGYLTMDTLG ALVFGIVIAT AIRDRGISDS RLVTRYSMIA GVIAATGLSL 
241:	VYLALFYLGA TSQGIAGDAQ NGVQILTAYV QQTFGVSGSL LLAVVITLAC LTTAVGLITA 
301:	CGEFFSDLLP VSYKTVVIVF SLFSLLVANQ GLTQLISLSV PVLVGLYPLA IVLIALSLFD 
361:	RLWVSAPRVF VPVMIVALLF GIVDGLGAAK LNGWVPDVFA KLPLADQSLG WLLPVSIALV 
421:	LAVVCDRLLG KPREAVA