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2.A.26.1.2
Ile/Val:H+ symporter

Accession Number:P25185
Protein Name:BraZ aka PA1971
Length:437
Molecular Weight:45274.00
Species:Pseudomonas aeruginosa [287]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Isoleucine, Valine, H+

Cross database links:

HEGENOM: HBG533860
RefSeq: NP_250661.1   
Entrez Gene ID: 879216   
Pfam: PF05525   
BioCyc: PAER208964:PA1971-MONOMER   
KEGG: pae:PA1971   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015658 F:branched-chain aliphatic amino acid transme...
GO:0015803 P:branched-chain aliphatic amino acid transport

References (2)

[1] “Isolation of the braZ gene encoding the carrier for a novel branched-chain amino acid transport system in Pseudomonas aeruginosa PAO.”  Hoshino T.et.al.   1900503
[2] “Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen.”  Stover C.K.et.al.   10984043

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MNALKGRDIL ALGFMTFALF VGAGNIIFPP IVGLQSGPHV WLAALGFLIT AVGLPVITVI 
61:	ALAKVGGSVD ALSHPIGRYA GGLLAAVCYL AVGPLFAIPR TATVSFEVGV VPLLGESGTA 
121:	LFVYSLAYFL LALAISLYPG RLLDTVGRFL APLKILALAI LGVAAFLWPA GPIGTAQPEY 
181:	TQAAFSQGFV NGYLTMDTLA ALVFGIVIVN AIRSRGVQSP RLITRYAIVA GLIAGVGLVL 
241:	VYVSLFRLGA GSHAIAADAS NGAAVLHAYV QHTFGSLGSS FLAGLIALAC LVTAVGLTCA 
301:	CAEYFCQRLP LSYRSLVIIL AGFSFIVSNL GLTKLIQVSI PVLTAIYPPC IVLVALSFCI 
361:	GLWHSATRIL APVMLVSLAF GVLDALKAAG LGQDFPQWLL HLPLAEQGLA WLIPSVATLA 
421:	ACSLVDRLLG KPAQVAA