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2.A.28.1.6
solute carrier family 10 (sodium/bile acid cotransporter family), member 5

Accession Number:Q5PT55
Protein Name:Sodium/bile acid cotransporter 5
Length:438
Molecular Weight:48871.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:9
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate bile acids, Na+

Cross database links:

Genevestigator: Q5PT55 Q5PT55
eggNOG: COG0385 COG0385
HEGENOM: HOG000037944 HOG000037944
Entrez Gene ID: 347051   
Pfam: PF01758   
KEGG: hsa:347051    hsa:347051   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0008508 F:bile acid:sodium symporter activity

References (4)

[1] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[2] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[3] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[4] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MIRKLFIVLL LLLVTIEEAR MSSLSFLNIE KTEILFFTKT EETILVSSSY ENKRPNSSHL 
61:	FVKIEDPKIL QMVNVAKKIS SDATNFTINL VTDEEGETNV TIQLWDSEGR QERLIEEIKN 
121:	VKVKVLKQKD SLLQAPMHID RNILMLILPL ILLNKCAFGC KIELQLFQTV WKRPLPVILG 
181:	AVTQFFLMPF CGFLLSQIVA LPEAQAFGVV MTCTCPGGGG GYLFALLLDG DFTLAILMTC 
241:	TSTLLALIMM PVNSYIYSRI LGLSGTFHIP VSKIVSTLLF ILVPVSIGIV IKHRIPEKAS 
301:	FLERIIRPLS FILMFVGIYL TFTVGLVFLK TDNLEVILLG LLVPALGLLF GYSFAKVCTL 
361:	PLPVCKTVAI ESGMLNSFLA LAVIQLSFPQ SKANLASVAP FTVAMCSGCE MLLIILVYKA 
421:	KKRCIFFLQD KRKRNFLI