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2.A.28.1.8
P3 protein (Solute carrier family 10 member 3)

Accession Number:P09131
Protein Name:P3 protein
Length:477
Molecular Weight:50333.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Unknown

Cross database links:

Genevestigator: P09131
eggNOG: COG0385
HEGENOM: HOG000037944
Entrez Gene ID: 8273   
Pfam: PF01758   
KEGG: hsa:8273   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0008508 F:bile acid:sodium symporter activity
GO:0015711 P:organic anion transport
GO:0032526 P:response to retinoic acid

References (4)

[1] “CpG islands of the X chromosome are gene associated.”  Alcalay M.et.al.   3186440
[2] “Long-range sequence analysis in Xq28: thirteen known and six candidate genes in 219.4 kb of high GC DNA between the RCP/GCP and G6PD loci.”  Chen E.Y.et.al.   8733135
[3] “The DNA sequence of the human X chromosome.”  Ross M.T.et.al.   15772651
[4] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MVLMQDKGSS QQWPGLGGEG GGTGPLSMLR AALLLISLPW GAQGTASTSL STAGGHTVPP 
61:	TGGRYLSIGD GSVMEFEFPE DSEGIIVISS QYPGQANRTA PGPMLRVTSL DTEVLTIKNV 
121:	SAITWGGGGG FVVSIHSGLA GLAPLHIQLV DAHEAPPTLI EERRDFCIKV SPAEDTPATL 
181:	SADLAHFSEN PILYLLLPLI FVNKCSFGCK VELEVLKGLM QSPQPMLLGL LGQFLVMPLY 
241:	AFLMAKVFML PKALALGLII TCSSPGGGGS YLFSLLLGGD VTLAISMTFL STVAATGFLP 
301:	LSSAIYSRLL SIHETLHVPI SKILGTLLFI AIPIAVGVLI KSKLPKFSQL LLQVVKPFSF 
361:	VLLLGGLFLA YRMGVFILAG IRLPIVLVGI TVPLVGLLVG YCLATCLKLP VAQRRTVSIE 
421:	VGVQNSLLAL AMLQLSLRRL QADYASQAPF IVALSGTSEM LALVIGHFIY SSLFPVP