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2.A.29.1.3
Adenine nucleotide transporter, ANT, or ATP:ADP carrier AAC1 (one of three paralogues).  Transports heme and heme precursor protoporphyrin IX (PP IX) as well as ATP and ADP (Azuma et al. 2008).

Accession Number:P04710
Protein Name:ADP/ATP translocase 1
Length:309
Molecular Weight:34121.00
Species:Saccharomyces cerevisiae (Baker's yeast) [4932]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Mitochondrion inner membrane1 / Multi-pass membrane protein2
Substrate Adenine, ATP, ADP, Heme, Heme precursor

Cross database links:

Genevestigator: P04710
eggNOG: fuNOG06875
HEGENOM: HBG610399
DIP: DIP-2551N
RefSeq: NP_013772.1   
Entrez Gene ID: 855078   
Pfam: PF00153   
KEGG: sce:YMR056C   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005743 C:mitochondrial inner membrane
GO:0005471 F:ATP:ADP antiporter activity
GO:0005488 F:binding
GO:0009060 P:aerobic respiration
GO:0006783 P:heme biosynthetic process
GO:0015886 P:heme transport
GO:0006839 P:mitochondrial transport
GO:0055085 P:transmembrane transport

References (3)

[1] “Sequences required for delivery and localization of the ADP/ATP translocator to the mitochondrial inner membrane.”  Adrian G.S.et.al.   3023860
[2] “The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII.”  Bowman S.et.al.   9169872
[3] “S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function.”  Hoyt M.A.et.al.   1651171

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSHTETQTQQ SHFGVDFLMG GVSAAIAKTG AAPIERVKLL MQNQEEMLKQ GSLDTRYKGI 
61:	LDCFKRTATH EGIVSFWRGN TANVLRYFPT QALNFAFKDK IKSLLSYDRE RDGYAKWFAG 
121:	NLFSGGAAGG LSLLFVYSLD YARTRLAADA RGSKSTSQRQ FNGLLDVYKK TLKTDGLLGL 
181:	YRGFVPSVLG IIVYRGLYFG LYDSFKPVLL TGALEGSFVA SFLLGWVITM GASTASYPLD 
241:	TVRRRMMMTS GQTIKYDGAL DCLRKIVQKE GAYSLFKGCG ANIFRGVAAA GVISLYDQLQ 
301:	LIMFGKKFK