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2.A.29.1.4
The Hydrogenosome ADP/ATP carrier (Van der Giezen et al., 2002)

Accession Number:Q8TFA7
Protein Name:ADP/ATP carrier
Length:308
Molecular Weight:33695.00
Species:Neocallimastix frontalis (Rumen fungus) [4757]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Mitochondrion inner membrane1 / Multi-pass membrane protein2
Substrate ATP, ADP

Cross database links:

Pfam: PF00153   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005743 C:mitochondrial inner membrane
GO:0005488 F:binding
GO:0005215 F:transporter activity
GO:0055085 P:transmembrane transport

References (1)

[1] “Conserved properties of hydrogenosomal and mitochondrial ADP/ATP carriers: a common origin for both organelles.”  van der Giezen M.et.al.   11847105

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MAQKKQQQKL GFYEDFLLAG VSATISKTAA APLERVKLLV QNQGEMLKSG RLATPYKGIG 
61:	DCFVRVAKEE GIASFWRGNG ANIIRYFPTQ ALNIAFKERI KNAFAVDKEK EGYAKWLVAN 
121:	IASGGAGGAL SQVFVYSLDY ARTRLANDAK SANGGERQYK GLIDVYKKTY KADGIAGLYR 
181:	GFTLSCVGIM VYRGLYFGLY DSMKPLLKNL GMEGSFAASF ILGWGVTTVA GIASYPIDTI 
241:	RRRMMMTSGE AVKYKSSIDC AKQVMQKEGV QAFFKGCGAN ILRGVAGAGV LSGFDKIKEV 
301:	YINWRIKN