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2.A.29.1.5
ADP (Km = 40 µM)/ATP (Km = 100 µM) antiporter, ACC1 (three isoforms, AAC1, 2 and 3 were characterized where AAC3 has higher affinities (10-22 µM) (Haferkamp et al., 2002).

Accession Number:P31167
Protein Name:ADP,ATP carrier protein 1, mitochondrial aka ACC1 aka ANT1
Length:381
Molecular Weight:41476.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Mitochondrion inner membrane1 / Multi-pass membrane protein2
Substrate ADP, ATP

Cross database links:

Genevestigator: P31167
eggNOG: KOG0749
HEGENOM: HBG610399
RefSeq: NP_187470.1    NP_850541.1   
Entrez Gene ID: 820005   
Pfam: PF00153   
KEGG: ath:AT3G08580   

Gene Ontology

GO:0005618 C:cell wall
GO:0009941 C:chloroplast envelope
GO:0016021 C:integral to membrane
GO:0005743 C:mitochondrial inner membrane
GO:0005730 C:nucleolus
GO:0005886 C:plasma membrane
GO:0005773 C:vacuole
GO:0005471 F:ATP:ADP antiporter activity
GO:0005507 F:copper ion binding
GO:0015865 P:purine nucleotide transport
GO:0055085 P:transmembrane transport

References (5)

[1] “Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.”  Salanoubat M.et.al.   11130713
[2] “Empirical analysis of transcriptional activity in the Arabidopsis genome.”  Yamada K.et.al.   14593172
[3] “Complementary DNA sequence of an adenylate translocator from Arabidopsis thaliana.”  Saint-Guily A.et.al.   16653021
[4] “Further progress towards a catalogue of all Arabidopsis genes: analysis of a set of 5000 non-redundant ESTs.”  Cooke R.et.al.   8580968
[5] “Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.”  Heazlewood J.L.et.al.   14671022

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MVDQVQHPTI AQKAAGQFMR SSVSKDVQVG YQRPSMYQRH ATYGNYSNAA FQFPPTSRML 
61:	ATTASPVFVQ TPGEKGFTNF ALDFLMGGVS AAVSKTAAAP IERVKLLIQN QDEMIKAGRL 
121:	SEPYKGIGDC FGRTIKDEGF GSLWRGNTAN VIRYFPTQAL NFAFKDYFKR LFNFKKDRDG 
181:	YWKWFAGNLA SGGAAGASSL LFVYSLDYAR TRLANDAKAA KKGGGGRQFD GLVDVYRKTL 
241:	KTDGIAGLYR GFNISCVGII VYRGLYFGLY DSVKPVLLTG DLQDSFFASF ALGWVITNGA 
301:	GLASYPIDTV RRRMMMTSGE AVKYKSSLDA FKQILKNEGA KSLFKGAGAN ILRAVAGAGV 
361:	LSGYDKLQLI VFGKKYGSGG A