TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.29.10.1
Flavin adenine dinucleotide (FAD) carrier (FADC; FLX1) (catalyzes FAD export from the mitochondrion) (Bafunno et al., 2004)

Accession Number:P40464
Protein Name:FLX1 aka YIL134W
Length:311
Molecular Weight:34409.00
Species:Saccharomyces cerevisiae (Baker's yeast) [4932]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Mitochondrion inner membrane1 / Multi-pass membrane protein2
Substrate FAD

Cross database links:

Genevestigator: P40464
eggNOG: fuNOG08773
HEGENOM: HBG735918
DIP: DIP-5662N
RefSeq: NP_012132.1   
Entrez Gene ID: 854672   
Pfam: PF00153   
KEGG: sce:YIL134W   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005743 C:mitochondrial inner membrane
GO:0005488 F:binding
GO:0015230 F:FAD transmembrane transporter activity
GO:0015883 P:FAD transport
GO:0055085 P:transmembrane transport

References (3)

[1] “FLX1 codes for a carrier protein involved in maintaining a proper balance of flavin nucleotides in yeast mitochondria.”  Tzagoloff A.et.al.   8631763
[2] “The nucleotide sequence of Saccharomyces cerevisiae chromosome IX.”  Churcher C.M.et.al.   9169870
[3] “Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae.”  Hu Y.et.al.   17322287

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MVDHQWTPLQ KEVISGLSAG SVTTLVVHPL DLLKVRLQLS ATSAQKAHYG PFMVIKEIIR 
61:	SSANSGRSVT NELYRGLSIN LFGNAIAWGV YFGLYGVTKE LIYKSVAKPG ETQLKGVGND 
121:	HKMNSLIYLS AGASSGLMTA ILTNPIWVIK TRIMSTSKGA QGAYTSMYNG VQQLLRTDGF 
181:	QGLWKGLVPA LFGVSQGALY FAVYDTLKQR KLRRKRENGL DIHLTNLETI EITSLGKMVS 
241:	VTLVYPFQLL KSNLQSFRAN EQKFRLFPLI KLIIANDGFV GLYKGLSANL VRAIPSTCIT 
301:	FCVYENLKHR L