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2.A.29.10.3
Chloroplast folate/folate derivative transporter, AtFOLT1 (Bedhomme et al., 2005; Haferkamp and Schmitz-Esser 2012)

Accession Number:Q4A3R4
Protein Name:Folt1
Length:308
Molecular Weight:34129.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate folate

Cross database links:

Genevestigator: Q4A3R4
eggNOG: KOG0764
Pfam: PF00153   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005743 C:mitochondrial inner membrane
GO:0005488 F:binding
GO:0005215 F:transporter activity
GO:0055085 P:transmembrane transport

References (1)

[1] “Folate metabolism in plants: an Arabidopsis homolog of the mammalianmitochondrial folate transporter mediates folate import into chloroplasts.”  Bedhomme M.et.al.   16055441

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MAASWQWENA TAGAVAGFAT VAAMHPLDVV RTRFQVNDGR GSSLPTYKNT AHAVFTIARL 
61:	EGLRGLYAGF FPAVIGSTVS WGLYFFFYGR AKQRYARGRD DEKLSPALHL ASAAEAGALV 
121:	CLCTNPIWLV KTRLQLQTPL HQTQPYSGLL DAFRTIVKEE GPRALYKGIV PGLVLVSHGA 
181:	IQFTAYEELR KIIVDLKERR RKSESTDNLL NSADYAALGG SSKVAAVLLT YPFQVIRARL 
241:	QQRPSTNGIP RYIDSLHVIR ETARYEGLRG FYRGLTANLL KNVPASSITF IVYENVLKLL 
301:	KQHPTTKD