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2.A.29.10.7
solute carrier family 25 (pyrimidine nucleotide carrier), member 33

Accession Number:Q9BSK2
Protein Name:Solute carrier family 25 member 33
Length:321
Molecular Weight:35375.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Mitochondrion inner membrane1 / Multi-pass membrane protein2
Substrate Pyrimidines

Cross database links:

Genevestigator: Q9BSK2 Q9BSK2
eggNOG: NOG301650 NOG301650
HEGENOM: HOG000188210 HOG000188210
Entrez Gene ID: 84275   
Pfam: PF00153   
KEGG: hsa:84275    hsa:84275   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005743 C:mitochondrial inner membrane
GO:0006810 P:transport

References (8)

[1] “HuBMSC-MCP, a novel member of mitochondrial carrier superfamily, enhances dendritic cell endocytosis.”  Wang B.et.al.   14715278
[2] “The DNA sequence and biological annotation of human chromosome 1.”  Gregory S.G.et.al.   16710414
[3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[4] “Fourteen novel human members of mitochondrial solute carrier family 25 (SLC25) widely expressed in the central nervous system.”  Haitina T.et.al.   16949250
[5] “HuBMSC-MCP, a novel member of mitochondrial carrier superfamily, enhances dendritic cell endocytosis.”  Wang B.et.al.   14715278
[6] “The DNA sequence and biological annotation of human chromosome 1.”  Gregory S.G.et.al.   16710414
[7] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[8] “Fourteen novel human members of mitochondrial solute carrier family 25 (SLC25) widely expressed in the central nervous system.”  Haitina T.et.al.   16949250

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MATGGQQKEN TLLHLFAGGC GGTVGAIFTC PLEVIKTRLQ SSRLALRTVY YPQVHLGTIS 
61:	GAGMVRPTSV TPGLFQVLKS ILEKEGPKSL FRGLGPNLVG VAPSRAVYFA CYSKAKEQFN 
121:	GIFVPNSNIV HIFSAGSAAF ITNSLMNPIW MVKTRMQLEQ KVRGSKQMNT LQCARYVYQT 
181:	EGIRGFYRGL TASYAGISET IICFAIYESL KKYLKEAPLA SSANGTEKNS TSFFGLMAAA 
241:	ALSKGCASCI AYPHEVIRTR LREEGTKYKS FVQTARLVFR EEGYLAFYRG LFAQLIRQIP 
301:	NTAIVLSTYE LIVYLLEDRT Q