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2.A.29.10.8
Mitochondrial nicotinamide adenine dinucleotide transporter 2, NDT2 (Mitochondrial NAD+ transporter 2) (Todisco et al. 2006).

Accession Number:P39953
Protein Name:Mitochondrial nicotinamide adenine dinucleotide transporter 2
Length:335
Molecular Weight:36961.00
Species:Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Mitochondrion inner membrane1 / Multi-pass membrane protein2
Substrate NAD+

Cross database links:

Genevestigator: P39953
eggNOG: NOG314559
HEGENOM: HOG000188210
DIP: DIP-4659N
Entrez Gene ID: 856712   
Pfam: PF00153   
KEGG: sce:YEL006W   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005743 C:mitochondrial inner membrane
GO:0005739 C:mitochondrion
GO:0051724 F:NAD transporter activity
GO:0055085 P:transmembrane transport

References (5)

[1] “The nucleotide sequence of Saccharomyces cerevisiae chromosome V.”  Dietrich F.S.et.al.   9169868
[2] “Phylogenetic classification of the mitochondrial carrier family of Saccharomyces cerevisiae.”  el Moualij B.et.al.   9178508
[3] “Global analysis of protein expression in yeast.”  Ghaemmaghami S.et.al.   14562106
[4] “Identification of the mitochondrial NAD+ transporter in Saccharomyces cerevisiae.”  Todisco S.et.al.   16291748
[5] “Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases.”  Smolka M.B.et.al.   17563356

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNNGDNKTTL ENSKNASLAN GNYAIPTKLN RLKKNADPRV AAISGALSGA LSAMLVCPFD 
61:	VAKTRLQAQG LQNMTHQSQH YKGFFGTFAT IFKDEGAAGL YKGLQPTVLG YIPTLMIYFS 
121:	VYDFCRKYSV DIFPHSPFLS NASSAITAGA ISTVATNPIW VVKTRLMLQT GIGKYSTHYK 
181:	GTIDTFRKII QQEGAKALYA GLVPALLGML NVAIQFPLYE NLKIRFGYSE STDVSTDVTS 
241:	SNFQKLILAS MLSKMVASTV TYPHEILRTR MQLKSDLPNT VQRHLLPLIK ITYRQEGFAG 
301:	FYSGFATNLV RTVPAAVVTL VSFEYSKKYL TTFFQ