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2.A.29.13.1
Succinate/fumarate antiporter, Sfc1, of 322 aas; essential for growth on ehtanol and acetate (Palmieri et al. 1997; Palmieri et al. 2006).

Accession Number:P33303
Protein Name:SFC1 aka ACR1 aka YJR095W aka J1921
Length:322
Molecular Weight:35340.00
Species:Saccharomyces cerevisiae (Baker's yeast) [4932]
Number of TMSs:2
Location1 / Topology2 / Orientation3: Mitochondrion inner membrane1 / Multi-pass membrane protein2
Substrate Succinate, Fumarate

Cross database links:

Genevestigator: P33303
eggNOG: fuNOG05719
HEGENOM: HBG735918
DIP: DIP-8019N
RefSeq: NP_012629.1   
Entrez Gene ID: 853558   
Pfam: PF00153   
KEGG: sce:YJR095W   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005743 C:mitochondrial inner membrane
GO:0005488 F:binding
GO:0005469 F:succinate:fumarate antiporter activity
GO:0015741 P:fumarate transport
GO:0015744 P:succinate transport
GO:0055085 P:transmembrane transport

References (4)

[1] “ACR1, a gene encoding a protein related to mitochondrial carriers, is essential for acetyl-CoA synthetase activity in Saccharomyces cerevisiae.”  Fernandez M.et.al.   7908717
[2] “Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X.”  Galibert F.et.al.   8641269
[3] “Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae.”  Hu Y.et.al.   17322287
[4] “Identification of the yeast ACR1 gene product as a succinate-fumarate transporter essential for growth on ethanol or acetate.”  Palmieri L.et.al.   9395087

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSQKKKASHP AINLMAGGTA GLFEALCCHP LDTIKVRMQI YRRVAGIEHV KPPGFIKTGR 
61:	TIYQKEGFLA LYKGLGAVVI GIIPKMAIRF SSYEFYRTLL VNKESGIVST GNTFVAGVGA 
121:	GITEAVLVVN PMEVVKIRLQ AQHLTPSEPN AGPKYNNAIH AAYTIVKEEG VSALYRGVSL 
181:	TAARQATNQG ANFTVYSKLK EFLQNYHQMD VLPSWETSCI GLISGAIGPF SNAPLDTIKT 
241:	RLQKDKSISL EKQSGMKKII TIGAQLLKEE GFRALYKGIT PRVMRVAPGQ AVTFTVYEYV 
301:	REHLENLGIF KKNDTPKPKP LK