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2.A.29.17.1
Peroxisomal ATP/ADP/AMP antiporter, Ant1 (Ypr128cp) (Palmieri et al. 2006).

Accession Number:Q06497
Protein Name:Ant1 aka YPR128C
Length:328
Molecular Weight:36367.00
Species:Saccharomyces cerevisiae (Baker's yeast) [4932]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Peroxisome membrane1 / Multi-pass membrane protein2
Substrate ATP, ADP, AMP

Cross database links:

Genevestigator: Q06497
eggNOG: fuNOG06729
HEGENOM: HBG329967
DIP: DIP-8825N
RefSeq: NP_015453.1   
Entrez Gene ID: 856246   
Pfam: PF00153   
KEGG: sce:YPR128C   

Gene Ontology

GO:0005779 C:integral to peroxisomal membrane
GO:0000295 F:adenine nucleotide transmembrane transporte...
GO:0005515 F:protein binding
GO:0015867 P:ATP transport
GO:0006635 P:fatty acid beta-oxidation
GO:0007031 P:peroxisome organization
GO:0015992 P:proton transport
GO:0055085 P:transmembrane transport

References (8)

[1] “The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.”  Bussey H.et.al.   9169875
[2] “Identification and functional reconstitution of the yeast peroxisomal adenine nucleotide transporter.”  Palmieri L.et.al.   11566870
[3] “Identification of a peroxisomal ATP carrier required for medium-chain fatty acid beta-oxidation and normal peroxisome proliferation in Saccharomyces cerevisiae.”  van Roermund C.W.T.et.al.   11390660
[4] “The peroxisomal transporter gene ANT1 is regulated by a deviant oleate response element (ORE): characterization of the signal for fatty acid induction.”  Rottensteiner H.et.al.   12071844
[5] “Global analysis of protein localization in budding yeast.”  Huh W.-K.et.al.   14562095
[6] “Global analysis of protein expression in yeast.”  Ghaemmaghami S.et.al.   14562106
[7] “The yeast peroxisomal adenine nucleotide transporter: characterization of two transport modes and involvement in DeltapH formation across peroxisomal membranes.”  Lasorsa F.M.et.al.   15219179
[8] “The peroxisomal lumen in Saccharomyces cerevisiae is alkaline.”  van Roermund C.W.T.et.al.   15316083

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MLTLESALTG AVASAMANIA VYPLDLSKTI IQSQVSPSSS EDSNEGKVLP NRRYKNVVDC 
61:	MINIFKEKGI LGLYQGMTVT TVATFVQNFV YFFWYTFIRK SYMKHKLLGL QSLKNRDGPI 
121:	TPSTIEELVL GVAAASISQL FTSPMAVVAT RQQTVHSAES AKFTNVIKDI YRENNGDITA 
181:	FWKGLRTGLA LTINPSITYA SFQRLKEVFF HDHSNDAGSL SAVQNFILGV LSKMISTLVT 
241:	QPLIVAKAML QSAGSKFTTF QEALLYLYKN EGLKSLWKGV LPQLTKGVIV QGLLFAFRGE 
301:	LTKSLKRLIF LYSSFFLKHN GQRKLAST