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2.A.29.2.5
2-oxodicarboxylate carrier 2 (ODC2) (transports the same substrates as human ODC except that 2-amino adipate is not transported while malate is) (Palmieri et al. 2006).

Accession Number:Q99297
Protein Name:YO7L aka ODC aka ODC2 aka YOR222W aka YOR50-12
Length:307
Molecular Weight:34007.00
Species:Saccharomyces cerevisiae (Baker's yeast) [4932]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Mitochondrion inner membrane1 / Multi-pass membrane protein2
Substrate 2-oxoadipate, 2-oxoglutarate, Pimelate, 2-oxopimleate, Oxaloacetate, Citrate, malate

Cross database links:

Genevestigator: Q99297
eggNOG: fuNOG04756
HEGENOM: HBG735918
DIP: DIP-5386N
RefSeq: NP_014865.1   
Entrez Gene ID: 854397   
Pfam: PF00153   
KEGG: sce:YOR222W   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005743 C:mitochondrial inner membrane
GO:0005488 F:binding
GO:0005310 F:dicarboxylic acid transmembrane transporter...
GO:0006839 P:mitochondrial transport
GO:0055085 P:transmembrane transport

References (3)

[1] “Sequence and analysis of a 33 kb fragment from the right arm of chromosome XV of the yeast Saccharomyces cerevisiae.”  Galisson F.et.al.   8840505
[2] “The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.”  Dujon B.et.al.   9169874
[3] “Identification in Saccharomyces cerevisiae of two isoforms of a novel mitochondrial transporter for 2-oxoadipate and 2-oxoglutarate.”  Palmieri L.et.al.   11013234

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSSDSNAKPL PFIYQFISGA VAGISELTVM YPLDVVKTRF QLEVTTPTAA AVGKQVERYN 
61:	GVIDCLKKIV KKEGFSRLYR GISSPMLMEA PKRATKFACN DQYQKIFKNL FNTNETTQKI 
121:	SIAAGASAGM TEAAVIVPFE LIKIRMQDVK SSYLGPMDCL KKTIKNEGIM GLYKGIESTM 
181:	WRNALWNGGY FGVIYQVRNS MPVAKTKGQK TRNDLIAGAI GGTVGTMLNT PFDVVKSRIQ 
241:	SVDAVSSAVK KYNWCLPSLL VIYREEGFRA LYKGFVPKVC RLAPGGSLML VVFTGMMNFF 
301:	RDLKYGH