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2.A.29.28.1
The thiamin pyrophosphate (TPP) carrier, TPC1 (Marobbio et al., 2002).

Accession Number:P53257
Protein Name:Putative mitochondrial carrier YGR096W
Length:314
Molecular Weight:35137.00
Species:Saccharomyces cerevisiae (Baker's yeast) [4932]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Mitochondrion inner membrane1 / Multi-pass membrane protein2
Substrate TPP

Cross database links:

Genevestigator: P53257
eggNOG: fuNOG06049
HEGENOM: HBG735918
RefSeq: NP_011610.1   
Entrez Gene ID: 852988   
Pfam: PF00153   
KEGG: sce:YGR096W   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005743 C:mitochondrial inner membrane
GO:0005515 F:protein binding
GO:0015234 F:thiamin transmembrane transporter activity
GO:0030974 P:thiamin pyrophosphate transport

References (6)

[1] “The nucleotide sequence of Saccharomyces cerevisiae chromosome VII.”  Tettelin H.et.al.   9169869
[2] “Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae.”  Hu Y.et.al.   17322287
[3] “Phylogenetic classification of the mitochondrial carrier family of Saccharomyces cerevisiae.”  el Moualij B.et.al.   9178508
[4] “The yeast mitochondrial transport proteins: new sequences and consensus residues, lack of direct relation between consensus residues and transmembrane helices, expression patterns of the transport protein genes, and protein-protein interactions with other proteins.”  Belenkiy R.et.al.   10930523
[5] “Identification and reconstitution of the yeast mitochondrial transporter for thiamine pyrophosphate.”  Marobbio C.M.T.et.al.   12411483
[6] “Global analysis of protein localization in budding yeast.”  Huh W.-K.et.al.   14562095

External Searches:

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Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MFKEEDSLRK GQNVAAWKTL LAGAVSGLLA RSITAPMDTI KIRLQLTPAN GLKPFGSQVM 
61:	EVARSMIKNE GIRSFWKGNI PGSLLYVTYG SAQFSSYSLF NRYLTPFGLE ARLHSLVVGA 
121:	FAGITSSIVS YPFDVLRTRL VANNQMHSMS ITREVRDIWK LEGLPGFFKG SIASMTTITL 
181:	TASIMFGTYE TIRIYCDENE KTTAAHKKWE LATLNHSAGT IGGVIAKIIT FPLETIRRRM 
241:	QFMNSKHLEK FSRHSSVYGS YKGYGFARIG LQILKQEGVS SLYRGILVAL SKTIPTTFVS 
301:	FWGYETAIHY LRMY