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2.A.29.29.1
The citrate/oxoglutarate carrier, Yhm2 (Castegna et al., 2010; Mayor et al., 1997). Ymh2 also transports oxaloacetate, succinate, and fumarate, but not malate or isocitrate. It may function in antioxidation (Castegna et al., 2010).

Accession Number:Q04013
Protein Name:Mitochondrial DNA replication protein YHM2
Length:314
Molecular Weight:34185.00
Species:Saccharomyces cerevisiae (Baker's yeast) [4932]
Number of TMSs:2
Location1 / Topology2 / Orientation3: Mitochondrion inner membrane1 / Multi-pass membrane protein2
Substrate Citrate, Oxoglutarate, Succinate, Fumarate

Cross database links:

Genevestigator: Q04013
eggNOG: fuNOG05091
HEGENOM: HBG330351
DIP: DIP-6370N
RefSeq: NP_013968.1   
Entrez Gene ID: 855282   
Pfam: PF00153   
KEGG: sce:YMR241W   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005743 C:mitochondrial inner membrane
GO:0042645 C:mitochondrial nucleoid
GO:0003677 F:DNA binding
GO:0005515 F:protein binding
GO:0005371 F:tricarboxylate secondary active transmembra...
GO:0000002 P:mitochondrial genome maintenance
GO:0055085 P:transmembrane transport
GO:0006842 P:tricarboxylic acid transport

References (5)

[1] “The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII.”  Bowman S.et.al.   9169872
[2] “A novel DNA-binding protein bound to the mitochondrial inner membrane restores the null mutation of mitochondrial histone Abf2p in Saccharomyces cerevisiae.”  Cho J.H.et.al.   9742088
[3] “Global analysis of protein localization in budding yeast.”  Huh W.-K.et.al.   14562095
[4] “Global analysis of protein expression in yeast.”  Ghaemmaghami S.et.al.   14562106
[5] “The proteome of Saccharomyces cerevisiae mitochondria.”  Sickmann A.et.al.   14576278

External Searches:

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  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MPSTTNTAAA NVIEKKPVSF SNILLGACLN LSEVTTLGQP LEVVKTTMAA NRNFTFLESV 
61:	KHVWSRGGIL GYYQGLIPWA WIEASTKGAV LLFVSAEAEY RFKSLGLNNF ASGILGGVTG 
121:	GVTQAYLTMG FCTCMKTVEI TRHKSASAGG VPQSSWSVFK NIYKKEGIRG INKGVNAVAI 
181:	RQMTNWGSRF GLSRLVEDGI RKITGKTNKD DKLNPFEKIG ASALGGGLSA WNQPIEVIRV 
241:	EMQSKKEDPN RPKNLTVGKT FKYIYQSNGL KGLYRGVTPR IGLGIWQTVF MVGFGDMAKE 
301:	FVARMTGETP VAKH