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2.A.29.3.3
The uncoupling protein, UCP1 or PUMP (functions to relieve oxidative stress, and to allow efficient photosynthesis (Sweetlove et al., 2006).  In spome plants, it is activated in response to cold stress and may control reactive oxygen species (Valente et al. 2012).

Accession Number:O65623
Protein Name:Plant uncoupling mitochondrial protein aka PUMP aka UCP1
Length:306
Molecular Weight:32704.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:3
Location1 / Topology2 / Orientation3: Mitochondrion inner membrane1 / Multi-pass membrane protein2
Substrate Unknown

Cross database links:

Genevestigator: O65623
eggNOG: KOG0753
Pfam: PF00153   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005739 C:mitochondrion
GO:0005488 F:binding
GO:0006839 P:mitochondrial transport
GO:0055085 P:transmembrane transport

References (1)

[1] “AtPUMP: an Arabidopsis gene encoding a plant uncoupling mitochondrial protein.”  Maia I.G.et.al.   9662458

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MVAAGKSDLS LPKTFACSAF AACVGEVCTI PLDTAKVRLQ LQKSALAGDV TLPKYRGLLG 
61:	TVGTIAREEG LRSLWKGVVP GLHRQCLFGG LRIGMYEPVK NLYVGKDFVG DVPLSKKILA 
121:	GLTTGALGIM VANPTDLVKV RLQAEGKLAA GAPRRYSGAL NAYSTIVRQE GVRALWTVLG 
181:	PNVARNAIIN AAELASYDQV KETILKIPGF TDNVVTHILS GLGAGFFAVC IGSPVDVVKS 
241:	RMMGDSGAYK GTIDCFVKTL KSDGPMAFYK GFIPNFGRLG SWNVIMFLTL EQAKKYVREL 
301:	DASKRN