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2.A.29.4.1
Phosphate carrier

Accession Number:P12234
Protein Name:MPCP aka SLC25A3 aka PHC
Length:362
Molecular Weight:40140.00
Species:Bos taurus (Bovine) [9913]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Mitochondrion inner membrane1 / Multi-pass membrane protein2
Substrate phosphate

Cross database links:

eggNOG: maNOG06897
RefSeq: NP_777082.1   
Entrez Gene ID: 282477   
Pfam: PF00153   
KEGG: bta:282477   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005743 C:mitochondrial inner membrane
GO:0005488 F:binding
GO:0015293 F:symporter activity
GO:0055085 P:transmembrane transport

References (4)

[1] “The sequences of human and bovine genes of the phosphate carrier from mitochondria contain evidence of alternatively spliced forms.”  Dolce V.et.al.   8144629
[2] “Sequence of the bovine mitochondrial phosphate carrier protein: structural relationship to ADP/ATP translocase and the brown fat mitochondria uncoupling protein.”  Runswick M.J.et.al.   3038521
[3] “Sequence of the N-terminal formic acid fragment and location of the N-ethylmaleimide-binding site of the phosphate transport protein from beef heart mitochondria.”  Kolbe H.V.J.et.al.   4066697
[4] “Transmembrane topography of the mitochondrial phosphate carrier explored by peptide-specific antibodies and enzymatic digestion.”  Capobianco L.et.al.   2036364

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MYSSVVHLAR ANPFNAPHLQ LVHDGLAGPR SDPAGPPGPP RRSRNLAAAA VEEQYSCDYG 
61:	SGRFFILCGL GGIISCGTTH TALVPLDLVK CRMQVDPQKY KSIFNGFSVT LKEDGFRGLA 
121:	KGWAPTFIGY SLQGLCKFGF YEVFKVLYSN MLGEENAYLW RTSLYLAASA SAEFFADIAL 
181:	APMEAAKVRI QTQPGYANTL RDAAPKMYKE EGLKAFYKGV APLWMRQIPY TMMKFACFER 
241:	TVEALYKFVV PKPRSECSKP EQLVVTFVAG YIAGVFCAIV SHPADSVVSV LNKEKGSSAS 
301:	EVLKRLGFRG VWKGLFARII MIGTLTALQW FIYDSVKVYF RLPRPPPPEM PESLKKKLGY 
361:	TQ