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2.A.29.5.5
solute carrier family 25 (mitochondrial iron transporter), member 37, putative iron transporter, Mitoferrin-1

Accession Number:Q920G8
Protein Name:Mitoferrin-1
Length:338
Molecular Weight:37510.00
Species:Mus musculus (Mouse) [10090]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Mitochondrion inner membrane1 / Multi-pass membrane protein2
Substrate iron

Cross database links:

Genevestigator: Q920G8
eggNOG: NOG261622
HEGENOM: HOG000038810
Entrez Gene ID: 67712   
Pfam: PF00153   
KEGG: mmu:67712   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005743 C:mitochondrial inner membrane
GO:0005381 F:iron ion transmembrane transporter activity
GO:0055072 P:iron ion homeostasis
GO:0048250 P:mitochondrial iron ion transport

References (3)

[1] “Rapid decrease of RNA level of a novel mouse mitochondria solute carrier protein (Mscp) gene at 4-5 weeks of age.”  Li Q.-Z.et.al.   11845285
[2] “The transcriptional landscape of the mammalian genome.”  Carninci P.et.al.   16141072
[3] “Mitoferrin is essential for erythroid iron assimilation.”  Shaw G.C.et.al.   16511496

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MELRRGGVGN QAAGRRMDGD CRDGGCGSKD AGSEDYENLP TSASVSTHMT AGAMAGILEH 
61:	SIMYPVDSVK TRMQSLNPDP KARYTSIYGA LKRIMHTEGF WRPLRGLNVM MMGAGPAHAM 
121:	YFACYENMKR TLNDVFSHQG NSHLANGVAG SMATLLHDAV MNPAEVVKQR LQMYNSQHQS 
181:	AFSCIRTVWR TEGLGAFYRS YTTQLTMNIP FQSIHFITYE FLQEQVNPRR DYNPQSHIIS 
241:	GGLAGALAAA ATTPLDVCKT LLNTQENMAL SLANVSGRLS GMANAFRTVY QLNGLAGYFK 
301:	GIQARVIYQM PSTAISWSVY EFFKYILTKR QLENRTLY