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2.A.29.5.7
Mitoferrin-1 (Mitochondrial iron transporter 1) (Mitochondrial solute carrier protein) (Solute carrier family 25 member 37)

Accession Number:Q9NYZ2
Protein Name:Mitoferrin-1
Length:338
Molecular Weight:37323.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Mitochondrion inner membrane1 / Multi-pass membrane protein2
Substrate iron

Cross database links:

Genevestigator: Q9NYZ2
eggNOG: NOG261622
HEGENOM: HOG000171727
Entrez Gene ID: 51312   
Pfam: PF00153   
KEGG: hsa:51312   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005743 C:mitochondrial inner membrane
GO:0006811 P:ion transport
GO:0055072 P:iron ion homeostasis

References (5)

[1] “Rapid decrease of RNA level of a novel mouse mitochondria solute carrier protein (Mscp) gene at 4-5 weeks of age.”  Li Q.-Z.et.al.   11845285
[2] “Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning.”  Hu R.-M.et.al.   10931946
[3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[4] “The full-ORF clone resource of the German cDNA consortium.”  Bechtel S.et.al.   17974005
[5] “Automated phosphoproteome analysis for cultured cancer cells by two-dimensional nanoLC-MS using a calcined titania/C18 biphasic column.”  Imami K.et.al.   18187866

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MELRSGSVGS QAVARRMDGD SRDGGGGKDA TGSEDYENLP TSASVSTHMT AGAMAGILEH 
61:	SVMYPVDSVK TRMQSLSPDP KAQYTSIYGA LKKIMRTEGF WRPLRGVNVM IMGAGPAHAM 
121:	YFACYENMKR TLNDVFHHQG NSHLANGIAG SMATLLHDAV MNPAEVVKQR LQMYNSQHRS 
181:	AISCIRTVWR TEGLGAFYRS YTTQLTMNIP FQSIHFITYE FLQEQVNPHR TYNPQSHIIS 
241:	GGLAGALAAA ATTPLDVCKT LLNTQENVAL SLANISGRLS GMANAFRTVY QLNGLAGYFK 
301:	GIQARVIYQM PSTAISWSVY EFFKYFLTKR QLENRAPY