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2.A.29.8.10
Solute carrier family 25 member 47 (Hepatocellular carcinoma down-regulated mitochondrial carrier protein)

Accession Number:Q6Q0C1
Protein Name:Solute carrier family 25 member 47
Length:308
Molecular Weight:33435.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Mitochondrion inner membrane1 / Multi-pass membrane protein2
Substrate Unknown

Cross database links:

Genevestigator: Q6Q0C1
eggNOG: NOG263786
HEGENOM: HOG000168307
Entrez Gene ID: 283600   
Pfam: PF00153   
KEGG: hsa:283600   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005743 C:mitochondrial inner membrane
GO:0055085 P:transmembrane transport

References (4)

[1] “Cloning and identification of hepatocellular carcinoma down-regulated mitochondrial carrier protein, a novel liver-specific uncoupling protein.”  Tan M.G.K.et.al.   15322095
[2] “Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas.”  Yamada S.et.al.   15221005
[3] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[4] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MDFVAGAIGG VCGVAVGYPL DTVKVRIQTE PKYTGIWHCV RDTYHRERVW GFYRGLSLPV 
61:	CTVSLVSSVS FGTYRHCLAH ICRLRYGNPD AKPTKADITL SGCASGLVRV FLTSPTEVAK 
121:	VRLQTQTQAQ KQQRRLSASG PLAVPPMCPV PPACPEPKYR GPLHCLATVA REEGLCGLYK 
181:	GSSALVLRDG HSFATYFLSY AVLCEWLSPA GHSRPDVPGV LVAGGCAGVL AWAVATPMDV 
241:	IKSRLQADGQ GQRRYRGLLH CMVTSVREEG PRVLFKGLVL NCCRAFPVNM VVFVAYEAVL 
301:	RLARGLLT