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2.A.29.8.11
Mitochondrial glutamate carrier protein YMC2, of 329 aas and 6 TMSs. Ymc2p transports glutamate, and to a much lesser extent L-homocysteinesulfinate, but not other amino acids and tested metabolites. Transport was saturable, inhibited by mercuric chloride and dependent on the proton gradient across the proteoliposomal membrane.  It transport glutamate across the mitochondrial inner membrane and thereby play a role in intermediary metabolism, C1 metabolism and mitochondrial protein synthesis (Porcelli et al. 2018).  

Accession Number:P38087
Protein Name:Carrier protein YMC2, mitochondrial
Length:329
Molecular Weight:36555.00
Species:Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Mitochondrion inner membrane1 / Multi-pass membrane protein2
Substrate Unknown

Cross database links:

Genevestigator: P38087
eggNOG: NOG285985
HEGENOM: HOG000168307
Entrez Gene ID: 852401   
Pfam: PF00153   
KEGG: sce:YBR104W   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005743 C:mitochondrial inner membrane
GO:0005739 C:mitochondrion
GO:0005342 F:organic acid transmembrane transporter activity
GO:0006839 P:mitochondrial transport

References (4)

[1] “Analysis of a 70 kb region on the right arm of yeast chromosome II.”  Mannhaupt G.et.al.   7900426
[2] “Complete DNA sequence of yeast chromosome II.”  Feldmann H.et.al.   7813418
[3] “Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae.”  Hu Y.et.al.   17322287
[4] “Global analysis of protein expression in yeast.”  Ghaemmaghami S.et.al.   14562106

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSEEFPTPQL LDELEDQQKV TTPNEKRELS SNRVLKDIFA GTIGGIAQVL VGQPFDTTKV 
61:	RLQTATTRTT TLEVLRNLVK NEGVFAFYKG ALTPLLGVGI CVSVQFGVNE AMKRFFQNYN 
121:	ASKNPNMSSQ DVDLSRSNTL PLSQYYVCGL TGGVVNSFLA SPIEQIRIRL QTQTSNGGDR 
181:	EFKGPWDCIK KLKAQGGLMR GLFPTMIRAG HGLGTYFLVY EALVAREIGT GLTRNEIPPW 
241:	KLCLFGAFSG TMLWLTVYPL DVVKSIIQND DLRKPKYKNS ISYVAKTIYA KEGIRAFFKG 
301:	FGPTMVRSAP VNGATFLTFE LVMRFLGEE