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2.A.29.8.4
Carnitine carrier, CRC1.  Exchanges carnitine for acetylcarnitine (Palmieri et al. 2006).

Accession Number:Q12289
Protein Name:Mitochondrial carnitine carrier CRC1
Length:327
Molecular Weight:34754.00
Species:Saccharomyces cerevisiae (Baker's yeast) [4932]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Mitochondrion inner membrane1 / Multi-pass membrane protein2
Substrate Carnitine

Cross database links:

Genevestigator: Q12289
eggNOG: fuNOG07795
HEGENOM: HBG735918
DIP: DIP-4154N
RefSeq: NP_014743.1   
Entrez Gene ID: 854267   
Pfam: PF00153   
KEGG: sce:YOR100C   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005743 C:mitochondrial inner membrane
GO:0005488 F:binding
GO:0005476 F:carnitine:acyl carnitine antiporter activity
GO:0006631 P:fatty acid metabolic process
GO:0055085 P:transmembrane transport

References (5)

[1] “Identification of the mitochondrial carnitine carrier in Saccharomyces cerevisiae.”  Palmieri L.et.al.   10622748
[2] “DNA sequencing and analysis of 130 kb from yeast chromosome XV.”  Voss H.et.al.   9200815
[3] “The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.”  Dujon B.et.al.   9169874
[4] “Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae.”  Hu Y.et.al.   17322287
[5] “Molecular characterization of carnitine-dependent transport of acetyl-CoA from peroxisomes to mitochondria in Saccharomyces cerevisiae and identification of a plasma membrane carnitine transporter, Agp2p.”  van Roermund C.W.et.al.   10545096

External Searches:

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  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSSDTSLSES SLLKEESGSL TKSRPPIKSN PVRENIKSFV AGGVGGVCAV FTGHPFDLIK 
61:	VRCQNGQANS TVHAITNIIK EAKTQVKGTL FTNSVKGFYK GVIPPLLGVT PIFAVSFWGY 
121:	DVGKKLVTFN NKQGGSNELT MGQMAAAGFI SAIPTTLVTA PTERVKVVLQ TSSKGSFIQA 
181:	AKTIVKEGGI ASLFKGSLAT LARDGPGSAL YFASYEISKN YLNSRQPRQD AGKDEPVNIL 
241:	NVCLAGGIAG MSMWLAVFPI DTIKTKLQAS STRQNMLSAT KEIYLQRGGI KGFFPGLGPA 
301:	LLRSFPANAA TFLGVEMTHS LFKKYGI