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2.A.29.8.8
solute carrier family 25, member 48.  May be associated with Parkinson's disease (Gutiérrez-Aguilar and Baines 2013).

Accession Number:Q6ZT89
Protein Name:Solute carrier family 25 member 48
Length:311
Molecular Weight:33440.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Mitochondrion inner membrane1 / Multi-pass membrane protein2
Substrate Unknown

Cross database links:

Genevestigator: Q6ZT89 Q6ZT89
eggNOG: NOG274957 NOG274957
Entrez Gene ID: 153328   
Pfam: PF00153   
KEGG: hsa:153328    hsa:153328   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005743 C:mitochondrial inner membrane
GO:0005488 F:binding
GO:0055085 P:transmembrane transport

References (6)

[1] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[2] “The DNA sequence and comparative analysis of human chromosome 5.”  Schmutz J.et.al.   15372022
[3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[4] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[5] “The DNA sequence and comparative analysis of human chromosome 5.”  Schmutz J.et.al.   15372022
[6] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MGSFQLEDFA AGWIGGAASV IVGHPLDTVK TRLQAGVGYG NTLSCIRVVY RRESMFGFFK 
61:	GMSFPLASIA VYNSVVFGVF SNTQRFLSQH RCGEPEASPP RTLSDLLLAS MVAGVVSVGL 
121:	GGPVDLIKIR LQMQTQPFRD ANLGLKSRAV APAEQPAYQG PVHCITTIVR NEGLAGLYRG 
181:	ASAMLLRDVP GYCLYFIPYV FLSEWITPEA CTGPSPCAVW LAGGMAGAIS WGTATPMDVV 
241:	KSRLQADGVY LNKYKGVLDC ISQSYQKEGL KVFFRGITVN AVRGFPMSAA MFLGYELSLQ 
301:	AIRGDHAVTS P