TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.3.1.10
S-Methylmethionine permease, MmuP

Accession Number:Q47689
Protein Name:S-methylmethionine permease, MmuP
Length:467
Molecular Weight:50526.00
Species:Escherichia coli [83333]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate S-Methylmethionine, Methylmethionine

Cross database links:

Genevestigator: Q47689
EchoBASE: EB3126
EcoGene: EG13342
eggNOG: COG0833
HEGENOM: HBG492579
RefSeq: AP_000913.1    NP_414794.4   
Entrez Gene ID: 946284   
Pfam: PF00324   
BioCyc: EcoCyc:B0260-MONOMER    ECOL168927:B0260-MONOMER   
KEGG: ecj:JW5027    eco:b0260   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015171 F:amino acid transmembrane transporter activity
GO:0006865 P:amino acid transport
GO:0055085 P:transmembrane transport

References (3)

[1] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[2] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[3] “S-methylmethionine metabolism in Escherichia coli.”  Thanbichler M.et.al.   9882684

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MQTTQQNAPL KRTMKTRHLI MLSLGGVIGT GLFFNTGYII STTGAAGTLL AYLIGALVVW 
61:	LVMQCLGELS VAMPETGAFH VYAARYLGPA TGYTVAWLYW LTWTVALGSS FTAAGFCMQY 
121:	WFPQVPVWVW CVVFCAIIFG LNVISTRFFA EGEFWFSLVK VVTIIAFIIL GGAAIFGFIP 
181:	MQDGSPAPGL SNITAEGWFP HGGLPILMTM VAVNFAFSGT ELIGIAAGET ENPRKVIPVA 
241:	IRTTIARLII FFIGTVFVLA ALIPMQQVGV EKSPFVLVFE KVGIPYAADI FNFVILTAIL 
301:	SAANSGLYAS GRMLWSLSNE RTLPACFARV TKNGVPLTAL SVSMLGGVLA LFSSVVAPDT 
361:	VFVALSAISG FAVVAVWLSI CASHFVFRRR HLQQGKALSE LHYRAPWYPL VPVLGFVLCL 
421:	VACVGLAFDP AQRIALWCGL PFVALCYGAY FLTQPRNAKQ EPEHVAE