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2.A.3.1.12
Aromatic amino acid permease, AroP (Wehrmann et al., 1995)

Accession Number:Q46065
Protein Name:Aromatic amino acid transport protein aka AroP
Length:463
Molecular Weight:49268.00
Species:Corynebacterium glutamicum (Brevibacterium flavum) [1718]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate tryptophan, phenylalanine, Histidine, tyrosine

Cross database links:

HEGENOM: HBG492579
RefSeq: NP_600335.2    YP_225399.1   
Entrez Gene ID: 1019092    3343787   
Pfam: PF00324   
BioCyc: CGLU196627:CG1257-MONOMER   
KEGG: cgb:cg1257    cgl:NCgl1062   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015171 F:amino acid transmembrane transporter activity
GO:0006865 P:amino acid transport
GO:0055085 P:transmembrane transport

References (2)

[1] “Functional analysis of sequences adjacent to dapE of Corynebacterium glutamicum reveals the presence of aroP, which encodes the aromatic amino acid transporter.”  Wehrmann A.et.al.   7592354
[2] “The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins.”  Kalinowski J.et.al.   12948626

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MAKSNEGLGT GLRTRHLTMM GLGSAIGAGL FLGTGVGIRA AGPAVLLAYI IAGAIVVLVM 
61:	QMLGEMAAAR PASGSFSRYG EDAFGHWAGF SLGWLYWFML IMVMGAEMTG AAAIMGAWFG 
121:	VEPWIPSLVC VVFFAVVNLV AVRGFGEFEY WFAFIKVAVI IAFLIIGIAL IFGWLPGSTF 
181:	VGTSNFIGDH GFMPNGISGV AAGLLAVAFA FGGIEIVTIA AAESDKPREA ISLAVRAVIW 
241:	RISVFYLGSV LVITFLMPYE SINGADTAAE SPFTQILAMA NIPGTVGFME AIIVLALLSA 
301:	FNAQIYATSR LVFSMANRQD APRVFSKLST SHVPTNAVLL SMFFAFVSVG LQYWNPAGLL 
361:	DFLLNAVGGC LIVVWAMITL SQLKLRKELQ ANDEISTVRM WAHPWLGILT LVLLAGLVAL 
421:	MLGDAASRSQ VYSVAIVYGF LVLLSFVTVN SPLRGGRTPS DLN