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2.A.3.1.21
Serine uptake transporter, SerP1, of 259 aas and 12 TMSs (Trip et al. 2013). L-serine is the highest affinity substrate (Km = 18 μM), but SerP1 also transports L-threonine and L-cysteine (Km values = 20 - 40 μM).  Does not transport D-serine (Noens and Lolkema 2015). The encoding gene is adjacent to a paralogue (serP2) with broad specificity for D- and L-small semipolar amino acids and glycine (see TC# 2.A.3.1.20).

Accession Number:F2HQ25
Protein Name:YdgC protein
Length:459
Molecular Weight:51412.00
Species:Lactococcus lactis subsp. lactis (strain CV56) [929102]
Number of TMSs:12
Substrate L-Serine, L-threonine, L-cysteine

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  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MENLQEKHEA QRGLQNRHIQ LIAIAGTIGT GLFLGAGKTI QMTGPSVIFA YILIGIAMFF 
61:	FLRTIGEMLY NDPSQHSFLN FVTKYSGVRT GYFTQWSYWL VIVFVCISEL TAIGTYIQFW 
121:	LPQVPLWLIE IVMLALLFGL NTLNSRFFGE TEFWFAMIKV AAIIGMIVTA IILVAGNFHY 
181:	STVLSGKTVH DSASLSNIFD GFQLFPHGAW NFVGALQMVM FAFTSMEFIG MTAAETVNPK 
241:	KSLPKAINQI PVRILLFYVG ALLAIMAIFN WHYIPADKSP FVMVFQLIGI KWAAALINFV 
301:	VLTSAASALN SSLFSATRNM YSLAQQHDKG RLTPFTKLSK AGIPINALYM ATALSLLAPV 
361:	LTLIPQIKNA FDFAASCTTN LFLVVYFITL YTYWQYRKSE DYNPKGFLTP KPQITVPFIV 
421:	AIFAIVFASL FFNADTFYPA LGAIVWTIFF GLYSHYKKI