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2.A.3.1.23
ProY of 457 aas and 12 TMSs.  96% identical to ProY of Salmonella enterica, a cryptic proline transporter in this organism (Liao et al. 1997).

Accession Number:P0AAE2
Protein Name:Proline-specific permease ProY
Length:457
Molecular Weight:50216.00
Species:Escherichia coli (strain K12) [83333]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Proline

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MESKNKLKRG LSTRHIRFMA LGSAIGTGLF YGSADAIKMA GPSVLLAYII GGIAAYIIMR 
61:	ALGEMSVHNP AASSFSRYAQ ENLGPLAGYI TGWTYCFEIL IVAIADVTAF GIYMGVWFPT 
121:	VPHWIWVLSV VLIICAVNLM SVKVFGELEF WFSFFKVATI IIMIVAGFGI IIWGIGNGGQ 
181:	PTGIHNLWSN GGFFSNGWLG MVMSLQMVMF AYGGIEIIGI TAGEAKDPEK SIPRAINSVP 
241:	MRILVFYVGT LFVIMSIYPW NQVGTAGSPF VLTFQHMGIT FAASILNFVV LTASLSAINS 
301:	DVFGVGRMLH GMAEQGSAPK IFSKTSRRGI PWVTVLVMTT ALLFAVYLNY IMPENVFLVI 
361:	ASLATFATVW VWIMILLSQI AFRRRLPPEE VKALKFKVPG GVATTIGGLI FLLFIIGLIG 
421:	YHPDTRISLY VGFAWIVVLL IGWMFKRRHD RQLAENQ