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2.A.3.10.21
The basic amino acid (canavanine sensitivity) transporter, Cat1 (Aspuria and Tamanoi, 2008).

Accession Number:Q9URZ4
Protein Name:Cat1
Length:580
Molecular Weight:63660.00
Species:Schizosaccharomyces pombe (Fission yeast) [4896]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Arginine, lysine, Histidine

Cross database links:

HEGENOM: HBG492579
RefSeq: NP_595008.2   
Entrez Gene ID: 2543573   
Pfam: PF00324   
KEGG: spo:SPAC869.11   

Gene Ontology

GO:0005737 C:cytoplasm
GO:0016021 C:integral to membrane
GO:0015181 F:arginine transmembrane transporter activity
GO:0015189 F:L-lysine transmembrane transporter activity
GO:0043091 P:L-arginine import
GO:0034226 P:lysine import
GO:0055085 P:transmembrane transport

References (2)

[1] “The genome sequence of Schizosaccharomyces pombe.”  Wood V.et.al.   11859360
[2] “Phosphoproteome analysis of fission yeast.”  Wilson-Grady J.T.et.al.   18257517

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MEPEYVSFSD KDTKSILNES KSSLKDVKPS LEEKSYITPG LVDDVEPKGK NFVVRFFDDF 
61:	KPAKATGEDG TALKRSLKSR HMQMISIGGA IGTGLYVGSG SSLADGGPAS VIINYSLIGI 
121:	MMFFIVYALG EMAVAYPVAG GFNTYATRFI DPAWGFAVSW NYFINYFVTF PLELTTCAIT 
181:	FRYWTDINSA AWISIFLVVI IIVNLFGVRA YGEVEFILST VKVVATFGFI ILAIIINCGG 
241:	VPTDHRGYIG GSIIKHKPFR HGFKGFCSVF TTAAFSFSGT EVIGLAAAEV DNPQKALPHA 
301:	VKQVFWRIAI FYVVSLILIG LLISPDDPNL MGNGSTSVSP FVLAIKEANI KGLPSVFNAV 
361:	IIISVVSVTN SSTYTAGRTL HGMANLKQAP SFFKYTDRLG RPLLAMIVVL LFGFFAYINE 
421:	ADKNGNDVSD TVFNWLLALS GLSNFFTWGS ICLCHIIFRL AFKKQGHSLK ELGFVSPMGI 
481:	WGSCIGLFFN ILCLMAQFYV SLFPIGGKPN ANDFFQGYLA APVTLAFFIG YKIYDRSHIP 
541:	SLDKLDITTG LKTYENLDEE EDEPTTASKR IFKKISSVFC