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2.A.3.8.2
L-type neutral amino acid transporter, ASUR4 (Na+-independent)

Accession Number:O13020
Protein Name:ASUR4
Length:507
Molecular Weight:55530.00
Species:Xenopus laevis (African clawed frog) [8355]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cytoplasm1 / Multi-pass membrane protein2
Substrate Amino acids

Cross database links:

Pfam: PF00324   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0015171 F:amino acid transmembrane transporter activity
GO:0006865 P:amino acid transport
GO:0055085 P:transmembrane transport

References (2)

[1] “Characterization of early aldosterone-induced RNAs in A6 kidney epithelia.”  Spindler B.et.al.   9178633
[2] “Amino-acid transport by heterodimers of 4F2hc/CD98 and members of a permease family.”  Mastroberardino L.et.al.   9751058

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MAADSVKRRQ SGASKTEEED RQAAEKMLHQ NGNAEPKSGD GGAVELQRTI TLVNGVAIIV 
61:	GTIIGSGIFV TPTGVLREAG SPGLSLLVWA VCGLFSIVGA LCYAELGTTI SKSGGDYAYV 
121:	LEVYGALPAF LKLWVELLII RPSSQYIVAL VFATYLLKPV FPTCPVPDDA AKIVACLCIL 
181:	LLTAINCYSV KAATRVQDAF AAAKLLALFL IIILGFVQLG KGGVEDLKPE RSFEGTSTNV 
241:	GQWVLALYSG LFAYGGWNYL NFVVEEMIEP YKNLPRAIII SMPIVTLVYV LTNLAYFTTL 
301:	TPEQMLNSEA VAVDFGNYHL GVMAWIIPVF VGLSCFGSVN GSLFTSSRLF FVGAREGHLP 
361:	SLLAMIHPRL LTPMPSLIFT CAMTLLYAFS NDIFSVINFF SFFNWLCVAL AIIGMMWLRY 
421:	KKPELERPIK VNILLPIFFI LACIFLIVVS FYMTPVECGI GFIIILTGVP VYFFGVWWQN 
481:	KPDWILHGIH SSTALLQKVM EAVPQES