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2.A.3.8.3
The schistosome neutral and cationic amino acid transporter, SPRM1lc (Na+-independent), (takes up phe, arg, lys, ala, gln, his, trp and leu; functions with SPRM1hc (TC# 8.A.9.3.1) (Krautz-Peterson et al., 2007)

Accession Number:Q26594
Protein Name:SPRM1 aka PRM1
Length:503
Molecular Weight:54298.00
Species:Schistosoma mansoni (Blood fluke) [6183]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cytoplasm1 / Multi-pass membrane protein2
Substrate phenylalanine, Arginine, lysine, Alanine, Glutamine, Histidine, tryptophan, Leucine

Cross database links:

RefSeq: XP_002579501.1   
Entrez Gene ID: 8350080   
Pfam: PF00324   
KEGG: smm:Smp_083990.   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0015171 F:amino acid transmembrane transporter activity
GO:0006865 P:amino acid transport
GO:0055085 P:transmembrane transport

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MGKSKKENKD SNATESVALK KEVSVLQGVS IVVGVIIGSG IFVSPVGVLK HTKSVGLSFI 
61:	MWAVTGLFST LGAIVYAELG VTIPRSGGEY VYILQTFGPL LAFLAFWITF VVIGSASCAA 
121:	NALIFAQYIL RPVYMDCVTP TIVIRTVAVL GLLLLCFVHC FSVKLATKVA VVFTACKVTA 
181:	LLIIIGFGLY YLGKGNVESF KNAFEDSEKS PGELALGFYQ GFWAFSGWNY LNFLTGEVKN 
241:	PGRTLPIVII LSLTTVTFIY ILTNVAYLAV LSPLEVLASE GSTAIAVSFA SRTMGVVGLV 
301:	MPALVGASVF GSINGEVFSI SRLAFTAGEE GHMPALLSMV NIDRLTPIPS ILIVVTLSVI 
361:	FQMFDDILYL IELTGFAFSV MSAMAVCSLL YIRRTNPEMN TSGFKLPIFF PVLYLIVDIA 
421:	IGILAIYQKP TDCAVSLGVM LLGVPVYLFG VVWKNKPRSM RSLIYGVTIT LQKVLKVVEQ 
481:	EKVSDIIELD GHLKPVDSQL DIS