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2.A.33.1.3
Na+/H+ antiporter NhaA (Sodium/proton antiporter NhaA)

Accession Number:Q39WP5
Protein Name:Na(+)/H(+) antiporter nhaA
Length:382
Molecular Weight:40374.00
Species:Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210) [269799]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Na+, H+

Cross database links:

eggNOG: COG3004
HEGENOM: HOG000218489
Entrez Gene ID: 3741296   
Pfam: PF06965   
KEGG: gme:Gmet_1089   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015297 F:antiporter activity
GO:0006885 P:regulation of pH
GO:0006814 P:sodium ion transport

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MRKPINLLRE FSVPLIAGVI TALAWANLDP RGYDALIHQP SFGGVSLHFL VNELFMVLFF 
61:	GIAAAEITQS CLPGGDLNPP RKAVNPLLAT LGGVIGPVLV YLSLNAVIGD PTLTKGWGIP 
121:	TATDIALAWL VARLVFGAGH PAVSFLLLLA VADDAIGLAI IAVFYPDPVH PTEPMWLFLT 
181:	VAGIVAAYIL RGARAKSYWP YVLVGGGLSW TGLFKAHLHP ALALVFIIPF LPHPPRESAH 
241:	LFEENPRDTS PLARFEHDWK IVVDFGLFLF GLANAGVRFS SVGTATWLVL TALLVGKTAG 
301:	ILTMGSLGKA LGFPLPDRVG FKELALTGLV AGMGLTVALF VAGVAFVDPD IEGAAKMGAL 
361:	LSGGVLPVAV ALGRILKVRR IP