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2.A.37.1.3
The K + efflux pump, KefB (Wei et al., 2007)

Accession Number:Q0ZAH7
Protein Name:NapA aka KefB
Length:661
Molecular Weight:71766.00
Species:Alkalimonas amylolytica [152573]
Number of TMSs:13
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate K+

Cross database links:

Pfam: PF00999    PF02080    PF02254   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005488 F:binding
GO:0003824 F:catalytic activity
GO:0015299 F:solute:hydrogen antiporter activity
GO:0008152 P:metabolic process
GO:0006813 P:potassium ion transport
GO:0055085 P:transmembrane transport

References (1)

[1] “Three putative cation/proton antiporters from the soda lake alkaliphile Alkalimonas amylolytica N10 complement an alkali-sensitive Escherichia coli mutant.”  Wei Y.et.al.   17600061

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MLLDGTLIQL LFLLGFMVFM VMLFQRAHIP ASIAYLLVGV LLGAHTAGPV ISEGYIHKIA 
61:	EFGIVFLLFT IGLRFSWQQI YQLRHTILGL GTAQVGLTTL LVALLLWAMG VASVVAFVIG 
121:	AVFAQSSTTI ISKQLLEQGE DQSRHGRLGI SLSVFQDITA VPFIIVIPVL GVAMAQDIAS 
181:	TLGMALFKAV LATALVVLVG RYLLRHLFHR VSSSDSAELF TLTVLLVCLA AAWLTQSLGL 
241:	SMAFGAFLAG MVMGETEFKL QVEAAIRPFR DVLLGIFFVS IGMLLDPMLL PEIGHIALAG 
301:	ALLLLLIKIV LVTALVLATG VALETAFRTG LILAVGGEFG FALLALALEG GTLDSRSSQI 
361:	ILTSVLLSMM LAVFLIRYNL QLSRFVVGRW IGQAAVSSEP FDDIEQHGLQ QHVVIAGFGR 
421:	IGQGVAQFLQ KEQVPYIGLD LDAARVKNAR LADVPVFYAD STDPDTLIAV GLAKARLLVI 
481:	SHEDLSAALT TLRHARTLHP DLPVIVRTRD ESHVAELRQA GATEVIPETI EAGMMLTSHV 
541:	LLMLNVPARR VNQLVQEQRI NRYQLLRQQF RGSADLLKTQ QQEQLKAVLL AEGSPAIDQS 
601:	LQMLDLAQYG IQLTELVRAH NRIEQPSLDM VLQENDVLVL FGSAEALEQA SLVLTHRLAA 
661:	D