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2.A.37.2.1
Na+:H+ antiporter, NapA

Accession Number:P26235
Protein Name:NapA
Length:383
Molecular Weight:41555.00
Species:Enterococcus hirae [1354]
Number of TMSs:13
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Na+, H+

Cross database links:

Pfam: PF00999   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015299 F:solute:hydrogen antiporter activity
GO:0006814 P:sodium ion transport
GO:0055085 P:transmembrane transport

References (2)

[1] “Cloning and disruption of a putative NaH-antiporter gene of Enterococcus hirae.”  Waser M.et.al.   1312090
[2] “The putative Na+/H+ antiporter (NapA) of Enterococcus hirae is homologous to the putative K+/H+ antiporter (KefC) of Escherichia coli.”  Reizer J.et.al.   1325937

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MEFIGILCLI LVATTIGSHI SRRFGIPAVI GQLLVGVLLG QAGLGWVHPN ILVHDFSEIG 
61:	VILLMFLAGL ESDLSLLKKY FKPGMFVALL GILFPVFFGW LTGEAFQVAN NEAIFFGIIL 
121:	AATSVSISVE VLKELNVVNT KEGSTILGAS VVDDILVVLV LSFSLSFLTG KSTSNLPLPL 
181:	LLLEQLFYFL FIFLLVKWIA PFLMSLAEKI YANSAIIIMS LVICLGMSYL ADLIGLSSVI 
241:	GAFFAGIAVS QTKVKHEVYN NVEALGYAVF IPVFFVSVGL EVDFSKFSEQ ILFILILTLV 
301:	AILTKLIGGY IGAKFSSFSS NSALMVGAGM ISRGEMALII LQIGQQSNLI ENHYYSPLVI 
361:	VVLLSTLISP LILKYFTKKV YAN