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2.A.39.3.2
Uracil/uridine permease

Accession Number:P05316
Protein Name:Fur4 aka YBR021W aka YBR0303
Length:633
Molecular Weight:71736.00
Species:Saccharomyces cerevisiae (Baker's yeast) [4932]
Number of TMSs:13
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Uracil, Uridine

Cross database links:

Genevestigator: P05316
eggNOG: fuNOG06698
HEGENOM: HBG333533
DIP: DIP-4892N
RefSeq: NP_009577.1   
Entrez Gene ID: 852309   
Pfam: PF02133   
KEGG: sce:YBR021W   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0045121 C:membrane raft
GO:0005886 C:plasma membrane
GO:0015505 F:uracil:cation symporter activity
GO:0055085 P:transmembrane transport
GO:0015857 P:uracil transport

References (4)

[1] “Primary structure of the uracil transport protein of Saccharomyces cerevisiae.”  Jund R.et.al.   3276521
[2] “The complete sequence of a 33 kb fragment on the right arm of chromosome II from Saccharomyces cerevisiae reveals 16 open reading frames, including ten new open reading frames, five previously identified genes and a homologue of the SCO1 gene.”  Smits P.H.M.et.al.   8091864
[3] “Complete DNA sequence of yeast chromosome II.”  Feldmann H.et.al.   7813418
[4] “A multidimensional chromatography technology for in-depth phosphoproteome analysis.”  Albuquerque C.P.et.al.   18407956

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MPDNLSLHLS GSSKRLNSRQ LMESSNETFA PNNVDLEKEY KSSQSNITTE VYEASSFEEK 
61:	VSSEKPQYSS FWKKIYYEYV VVDKSILGVS ILDSFMYNQD LKPVEKERRV WSWYNYCYFW 
121:	LAECFNINTW QIAATGLQLG LNWWQCWITI WIGYGFVGAF VVLASRVGSA YHLSFPISSR 
181:	ASFGIFFSLW PVINRVVMAI VWYSVQAYIA ATPVSLMLKS IFGKDLQDKI PDHFGSPNAT 
241:	TYEFMCFFIF WAASLPFLLV PPHKIRHLFT VKAVLVPFAS FGFLIWAIRR AHGRIALGSL 
301:	TDVQPHGSAF SWAFLRSLMG CMANFSTMVI NAPDFSRFSK NPNSALWSQL VCIPFLFSIT 
361:	CLIGILVTAA GYEIYGINYW SPLDVLEKFL QTTYNKGTRA GVFLISFVFA VAQLGTNISA 
421:	NSLSCGTDMS AIFPKFINIK RGSLFCAAMA LCICPWNLMA TSSKFTMALS AYAIFLSSIA 
481:	GVVCSDYFVV RRGYIKLTHI YSHQKGSFYM YGNRFGINWR ALAAYLCGVA PCLPGFIAEV 
541:	GAPAIKVSDG AMKLYYLSYW VGYGLSFSSY TALCYFFPVP GCPVNNIIKD KGWFQRWANV 
601:	DDFEEEWKDT IERDDLVDDN ISVYEHEHEK TFI